Evidence map›Paper›PMID 41706053›Full record

Trial reportEuropean journal of physical and rehabilitation medicine2026

The effect of early mobilization of post-cardiac surgery patients on delirium: a pilot study.

Jingyuan Xu, Weijie Yu, Yun Yu, Juan Zhou, Meng Deng, Wenchun Wang, Jie Jiang, Wei Chang, Yi Yang, Hailong Cao and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of physical and rehabilitation medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jingyuan XuJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Weijie YuDepartment of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Yun YuDepartment of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Juan ZhouDepartment of Cardiac Surgery, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Meng DengDepartment of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Wenchun WangDepartment of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Jie JiangDepartment of Cardiac Surgery, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Wei ChangJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Yi YangJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Hailong CaoDepartment of Cardiac Surgery, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Fengmei GuoJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China - 13813841261@139.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe best time to perform mobilization in patients after cardiac surgery is still unknown. Specifically, the efficacy and safety of initiating mobilization within the first 24 hours remain unclear.

aimWe evaluated the effect of early mobilization within 24 hours post cardiac surgery on the incidence of delirium.

designThis was a single-centered randomized pilot study.

settingTertiary teaching hospital. POPULATION: Adult post-cardiac surgery patients were randomized to early mobilization group or usual care group.

methodsIn the early mobilization group, sitting down with no support on a wheelchair for more than 30 minutes were implemented within 24 hours of intensive care unit (ICU) admission, then performed every day until day 7. In the usual care group, mobilization was performed after transferred to the cardiac surgery department, then performed every day until day 7. Screening for delirium by Confusion Assessment Method for the ICU (CAM-ICU) was performed on anesthesia recovery period, 8 hours after awakening, on the second day postsurgery, and every morning until 7 days. The primary outcome was the incidence of delirium during the first 7 days after randomization. The secondary outcomes included duration of delirium, mechanical ventilation time, length of ICU stay and in-hospital mortality.

resultsSixty patients were enrolled, 30 assigned to each group. No baseline difference was identified between the early mobilization group and usual care group. The incidence of delirium was 26.7%. In the early mobilization group, a trend toward a lower incidence of delirium on the second day was found, and the duration of delirium was significantly shorter. No severe adverse events were identified during the first mobilization time, which lasted for almost 40 minutes.

conclusionsEarly mobilization might be effective in reducing delirium incidence and duration for post-cardiac surgery patients, despite not significantly reducing its incidence. These preliminary findings should be tested in larger multicenter trials. CLINICAL REHABILITATION IMPACT: Early mobilization within 24 hours post-cardiac surgery might be effective in reducing delirium and is safe for post-cardiac surgery patients, which should be tested in larger multicenter trials.

Indexed as

Cardiac Surgical ProceduresDeliriumEarly AmbulationPostoperative CarePostoperative ComplicationsAgedFemaleHumansIncidenceIntensive Care UnitsLength of StayMaleMiddle AgedPilot ProjectsTreatment Outcome

Identifiers

PMID41706053
PMCPMC13168822

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.