Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Kyungsub Kim *Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.ORCID 0000-0003-2897-0220
Marcos Antonio Valdespino Diaz *Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.ORCID 0009-0006-8620-0530
Rowan M KarrDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0009-0008-9923-286X
Michele E MuscoloDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.ORCID 0009-0004-7653-0785
Lisa GoersDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-1585-8726
Truelian YuDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Tera C LevinDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-7883-8522
Jonathan N PrunedaDepartment of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0002-0304-4418
Cammie F LesserDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.ORCID 0000-0002-1702-6333
Funding
INFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1M
Shigella mediated regulation of epithelial cell inflammasomesR01AI169795 · NIAID · TUFTS UNIVERSITY BOSTON · PI CAMMIE LESSER · 2023 to 2026
$3.0M
Exploiting bacterial effector proteins to study human ubiquitin signalingR35GM142486 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Jonathan N Pruneda · 2021 to 2026
$2.6M
TIR domains and the ancestry of innate immunityR35GM150681 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Tera Catherine Levin · 2023 to 2026
Pyroptosis is an inflammatory cell death pathway that is a key defense mechanism of intestinal epithelial cells. To successfully establish an infection, intracytosolic gram-negative pathogens must block this host response. Indeed, a
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Differential targeting of human pyroptotic caspase-5 and caspase-4 by · full record | OpenQuestion