Evidence map›Paper›PMID 41705840›Full record

Trial reportMicrobiology spectrum2026

Preclinical and clinical evaluation of vancomycin plus delpazolid combination therapy for MRSA bacteremia: a multicenter, double-blinded, randomized, parallel design, phase IIa clinical trial.

Kyung-Hwa Park, Jongtak Jung, Sung Un Shin, Su Jin Jeong, Dae Won Park, Dong-Min Kim, Seong Jin Choi, Song Mi Moon, Jeong Su Park, Kyoung-Ho Song and 5 more

Abstract readClinical Trial, Phase IIRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kyung-Hwa Park *Department of Infectious Diseases, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea.ORCID 0000-0003-2836-6963
Jongtak Jung *Division of Infectious Diseases, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul, Korea.ORCID 0000-0003-3497-0796
Sung Un ShinDepartment of Infectious Diseases, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea.
Su Jin JeongDivision of Infectious Diseases, Department of Internal Medicine and AIDS Research Institute, Yonsei University College of Medicine, Seodaemun-gu, Korea.
Dae Won ParkDepartment of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Seoul, Korea.
Dong-Min KimDepartment of Internal Medicine, Chosun University Hospital, Gwangju, Korea.
Seong Jin ChoiDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Song Mi MoonDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Jeong Su ParkDepartment of Laboratory Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Kyoung-Ho SongDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.ORCID 0000-0002-4517-3840
Eu Suk KimDepartment of Laboratory Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.ORCID 0000-0001-7132-0157
Young Lag ChoLigaChem Biosciences Inc., Daejeon, Republic of Korea.
Seongman BaeDepartment of Internal Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID 0000-0001-6375-3657
Hong Bin KimDepartment of Laboratory Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.ORCID 0000-0001-6262-372X
Korea INfectious Diseases (KIND) Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methicillin-resistant IMPORTANCE: Methicillin-resistant

Indexed as

Anti-Bacterial AgentsBacteremiaMethicillin-Resistant Staphylococcus aureusOxazolidinonesStaphylococcal InfectionsVancomycinAdultAgedAnimalsDouble-Blind MethodDrug Therapy, CombinationFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedAnti-Bacterial AgentsdelpazolidOxazolidinonesVancomycinclinical trialcombination therapydelpazolidMRSA bacteremiavancomycin

Identifiers

PMID41705840
PMCPMC13055365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.