Evidence map›Paper›PMID 41705830›Full record

ArticleAntimicrobial agents and chemotherapy2026

Clinical outcomes with oral cephalosporins as definitive treatment of Enterobacterales bacteremia from a urinary source based on cefazolin minimum inhibitory concentration.

Lauren Kobasuk, Tamara Cisowska, Karen Howard, Christian Gabriel, Chaorong Wu, Hannah Imlay, Emily S Spivak, Kara Nazminia

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lauren KobasukDepartment of Pharmacy, University of Utah Health, Salt Lake City, Utah, USA.ORCID 0009-0001-1885-8238
Tamara CisowskaDepartment of Pharmacy, University of Utah Health, Salt Lake City, Utah, USA.ORCID 0000-0003-0707-5155
Karen HowardDepartment of Pharmacy, University of Utah Health, Salt Lake City, Utah, USA.
Christian GabrielDepartment of Pharmacy, University of Utah Health, Salt Lake City, Utah, USA.
Chaorong WuDepartment of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Hannah ImlayDepartment of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Emily S SpivakDepartment of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Kara NazminiaDepartment of Pharmacy, University of Utah Health, Salt Lake City, Utah, USA.ORCID 0000-0003-2937-6397

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cefazolin breakpoints differ for the treatment of Enterobacterales urinary tract infections and systemic infections. A retrospective, exploratory cohort study of 148 patients found no difference in 30-day treatment outcomes based on the blood culture cefazolin minimum inhibitory concentration (≤2 mcg/mL versus 4-16 mcg/mL) for patients transitioned to PO cephalosporins for the treatment of

Indexed as

Anti-Bacterial AgentsBacteremiaCefazolinCephalosporinsEnterobacteriaceae InfectionsUrinary Tract InfectionsAdministration, OralEnterobacteriaceaeEscherichia coliFirst Generation CephalosporinsHumansKlebsiella pneumoniaeMicrobial Sensitivity TestsProteus mirabilisRetrospective StudiesThird Generation CephalosporinsAnti-Bacterial AgentsCefazolinCephalosporinsFirst Generation CephalosporinsThird Generation CephalosporinscephalosporinsEnterobacterales bacteremia

Identifiers

PMID41705830
PMCPMC13041345

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.