Evidence map›Paper›PMID 41705828›Full record

ArticleAntimicrobial agents and chemotherapy2026

Yu-Lin Lee, Wei-Yao Wang, Yu-Tsung Huang, Mao-Wang Ho, Wen-Chien Ko, Po-Ren Hsueh

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Combating Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yu-Lin LeeDivision of Infectious Disease, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.ORCID 0000-0001-6346-082X
Wei-Yao WangDivision of Infectious Disease, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.
Yu-Tsung HuangDepartments of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0002-7805-4178
Mao-Wang HoDepartment of Internal Medicine, Division of Infectious Diseases, China Medical University Hospital, China Medical University, Taichung, Taiwan.
Wen-Chien KoDivision of Infectious Diseases, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.
Po-Ren HsuehDepartments of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0002-7502-9225

Funding

Pfizer Pharmaceutical ATLAS
6 · The paper itself

Abstract

Carbapenem-resistant Enterobacterales (CRE) pose significant treatment challenges. While ceftazidime-avibactam (CZA) is commonly used, resistance rates have been increasing. Aztreonam-avibactam (ATM-AVI) may represent a promising alternative. A total of 109,603 Enterobacterales isolates were collected from 307 sites across 63 countries between 2019 and 2023 as part of the Antimicrobial Testing Leadership and Surveillance (ATLAS) program. CRE were defined as isolates with a meropenem minimal inhibitory concentration (MIC) ≥2 mg/L. Susceptibility testing was conducted according to the Clinical and Laboratory Standards Institute (CLSI) 2025 guidelines, and β-lactamase genes were identified by multiplex PCR and sequencing. Of the total Enterobacterales isolates, 7,520 (7.6%) were identified as CRE, with

Indexed as

Anti-Bacterial AgentsAzabicyclo CompoundsAztreonamBacterial Proteinsbeta-LactamasesCarbapenem-Resistant EnterobacteriaceaeCeftazidimeEnterobacteriaceaeDrug CombinationsDrug Resistance, Multiple, BacterialHumansMicrobial Sensitivity TestsAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo CompoundsAztreonamaztreonam, avibactam drug combinationBacterial Proteinsbeta-LactamasescarbapenemaseCeftazidimeDrug Combinationsaztreonam–avibactamcarbapenem-resistant Enterobacteralesceftazidime–avibactammetallo-β-lactamase

Identifiers

PMID41705828
PMCPMC13041386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.