ArticleChemical senses2026
Response to Doty 2025, predicting odor from structure is useful.
Article in Chemical senses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Doty (Odors as cognitive constructs: history of odor classification and attempts to map odor percepts to physical and chemical parameters. 2025. Chem Senses 50:bjaf022) provides a thorough historical review of odor classification but underestimates recent advances in quantifying odor space. He argues that odor qualities are cognitive constructs that do not map well to physicochemical properties. While odor is indeed cognitively mediated, practical and predictive rules for olfaction exist and continue to improve. Therefore, we suggest that Doty's historical review should be read not as a eulogy for physicochemical modeling, but as a historical baseline that the field is now surpassing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.