ArticleReproductive medicine and biology
Analysis of Risk Factors Affecting Cumulative Live Birth in Couples With Unexplained Infertility Undergoing IVF/ICSI.
Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Empty Follicle Syndrome: Current Therapeutic Approaches and the Role of Triggering Agents in Assisted Reproductive Technology.Medical sciences (Basel, Switzerland) · 2026Review
- Analysis of Risk Factors Affecting Cumulative Live Birth in Couples With Unexplained Infertility Undergoing IVF/ICSI.Reproductive medicine and biologyArticle
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Authors and funding
7 authors.
Funding
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Abstract
Purpose: To identify the specific risk factors associated with unexplained infertility (UI) among infertile couples. Methods: We conducted a retrospective cohort study analyzing UI risk factors, focusing on 5465 infertile couples who completed their first full in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycle out of a total cohort of 62201 infertile couples. Results: Among 5465 UI couples, 3400 achieved a live birth (cumulative live birth rate = 62.2%). Multivariate logistic regression indicated the key negative predictors included: female age ≥ 35 years (odds ratio [OR]: 0.63; 95% confidence interval [CI]: 0.51-0.78; Conclusion: The prevalence of UI was 8.8% in our population, with 62.2% achieving CLB after one complete IVF/ICSI cycle. Female age and ovarian reserve indicators emerged as the main factors influencing oocyte yield, embryo acquisition, and CLB outcomes in UI patients.
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