ArticleTherapeutic advances in gastroenterology2026
Real-time guidance of lauromacrogol ablation for pancreatic cystic lesions using confocal laser endomicroscopy.
Article in Therapeutic advances in gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Image stitching for probe-based confocal laser endomicroscopy via a motion consistency constraint.Biomedical optics express · 2026Article
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11 authors.
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Abstract
Background: Needle-based confocal laser endomicroscopy (nCLE) can accurately identify the pathological types of pancreatic cystic lesions (PCLs), but there are no reports of real-time intraoperative guidance for lauromacrogol ablation (LA) therapy. Objectives: This study aimed to assess the diagnostic accuracy and safety of nCLE in identifying the candidates for LA in the same session as endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). Design: Prospective study. Methods: We performed a prospective study of patients with PCL who underwent EUS-FNA and nCLE at the First Medical Center of Chinese PLA General Hospital between February 2024 and June 2025. The diagnostic performance of nCLE in intraoperatively differentiating concomitant ablation-eligible lesions (CAELs) from concomitant ablation-ineligible lesions (CAILs) was evaluated and compared with that of EUS morphology and the cyst fluid string sign. Results: A total of 29 patients were enrolled in the study, and the mean size of the cyst was 34.1 ± 12.5 mm. The mean duration of EUS-nCLE was 4.61 min. EUS-nCLE identified CAELs with 94% sensitivity, 77% specificity, and 86% accuracy. The diagnostic accuracy of nCLE was superior to that of EUS morphology and the string sign (86% vs 66%, Conclusion: Confocal laser endomicroscopy demonstrates favorable real-time diagnostic performance for PCLs, allowing accurate assessment of the suitability for ablation during puncture and thereby avoiding the need for a repeat procedure.
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