ArticleChemical science2026
Modulating halide leaving-group trends through recognition by bisboranes.
Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Modulating the intrinsic leaving-group tendency of halides remains a long-standing challenge in synthetic chemistry. Herein, we reported dynamic anion recognition and demonstrated its application in nucleophilic substitution reactions, enabling an apparent reversal of the halide leaving-group tendency sequence. A bidentate Lewis acid-based platform was developed to selectively bind halide ions, forming host-guest complexes that were characterized by NMR spectroscopy and X-ray crystallography. Competitive experiments with the host molecule have revealed tunable binding affinities for the halides based on the cavity size of the bisboron center. Moreover, anion exchange experiments have demonstrated that the dynamic binding of halides is primarily influenced by their nucleophilicity and ion radius. The recognition of organohalides by diborane hosts induced a reversal of the leaving ability of Br
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.