ArticleCureus2026
Acute Portal Vein Thrombosis Associated With Anastrozole Therapy: A Report of a Rare Case.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Portal vein thrombosis (PVT) is a rare but potentially life-threatening condition that most often occurs in the setting of liver disease, malignancy, local inflammation, certain medications, or hypercoagulable disorders. We report a rare case of acute PVT in a 71-year-old woman with a history of breast cancer in remission who was receiving adjuvant anastrozole therapy and presented with abdominal pain. CT revealed extensive thrombosis involving the portal vein and superior mesenteric vein. The workup excluded malignancy recurrence and infection, revealing only heterozygous factor V Leiden. With no other clear cause identified, anastrozole was considered the most likely etiology. This case highlights the importance of recognizing aromatase inhibitors as potential contributors to venous thrombosis.
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