Evidence map›Paper›PMID 41704923›Full record

ArticleEFSA journal. European Food Safety Authority2026

Assessment of the feed additives tocopherol extracts from vegetable oils (1b306(i)), tocopherol-rich extracts from vegetable oils (delta rich) (1b306(ii)) and alpha-tocopherol (1b307) for all animal species for the renewal of their authorisation (ADM International Sàrl, DSM Nutritional Products Ltd., Europe-Asia Import Export GmbH., Vitiva d.o.o., Kaesler Nutrition GmbH, Kemin Nutrisurance Europe SRL, LUCTA S.A., Vitae Caps S.A.U/Kensing).

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba and 11 more

Abstract read
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
Roberto Edoardo Villa
Giovanna Azimonti
Eleftherios Bonos
Henrik Christensen
Mojca Durjava
Birgit Dusemund
Ronette Gehring
Boet Glandorf
Maryline Kouba
Marta López-Alonso
Francesca Marcon
Carlo Nebbia
Alena Pechová
Miguel Prieto-Maradona
Katerina Theodoridou
Jaume Galobart
Paola Manini
Piera Valeri
Maria Vittoria Vettori
Fabiola Pizzo

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of vitamin E in the forms of tocopherol extracts from vegetable oils, tocopherol-rich extracts from vegetable oils (delta rich) and alpha-tocopherol, as technological feed additives for all animal species. The additives are already authorised for use in all animal species without a specified minimum or maximum level. The applicant provided evidence that the additives currently on the market comply with the existing conditions of authorisation. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the additives remain safe for the target species, the consumer and the environment. Regarding user safety, the additives should be considered skin and respiratory sensitisers. Exposure of users by inhalation and dermal routes is considered a risk. The FEEDAP Panel cannot conclude on the eye irritation potential due to the lack of data. There is no need to assess the efficacy of the additives in the context of the renewal of the authorisation.

Indexed as

all animal speciesantioxidantefficacysafetytechnological additivestocopherol

Identifiers

PMID41704923
PMCPMC12907736

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.