Trial reportFrontiers in physiology2026
Real-time change in dynamic cerebral autoregulation after acupuncture at GB34 (Yanglingquan): a self-controlled study.
Trial report in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
12 authors.
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Abstract
Background: Few interventions have been proven to improve dynamic cerebral autoregulation (dCA). GB34 is a common acupoint for motor function treatment in the clinic. However, the effects of acupuncture on dCA have never been reported and whether acupuncture at GB34 can improve dCA is unknown. Methods: A self-controlled interventional study was conducted. Each participant randomly received two acupuncture interventions, including active acupuncture and sham acupuncture. Transcranial Doppler and servo-controlled finger photoplethysmography were used to record continuous cerebral blood flow velocity in the bilateral middle cerebral arteries and continuous blood pressure to assess dCA with transfer function analysis during acupuncture intervention. Results: Twenty healthy volunteers were enrolled. The left and right phase values in the low-frequency band after acupuncture treatment were significantly higher than baseline levels. Meanwhile, a reduction in heart rate was observed after acupuncture treatment. In contrast, no real-time changes were observed in any parameters after sham acupuncture intervention. Conclusion: The results suggested that treatment with acupuncture at GB34 increased dCA in young healthy volunteers. The increased dCA may contribute to the beneficial effects of acupuncture on cerebrovascular function. Clinical Trial Registration: https://www.chictr.org.cn/showproj.html?proj=121012, identifier ChiCTR2100042762.
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