Evidence map›Paper›PMID 41704803›Full record

ArticleIJID regions2026

Real-world effectiveness of oral cholera vaccine amid fragility: A case-control study from Eastern Sudan, 2024.

Ahmad Izzoddeen, Ali Abolgassim, Wesam Yousif, Emtiaz Atta Elhussein, Eymanne ElBushra, Dalya Eltayeb, Muntasir M O Elhassan, Hassan El-Bushra

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in IJID regions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ahmad IzzoddeenField Epidemiology Training Program, Federal Ministry of Health, Khartoum, Sudan.
Ali AbolgassimDG of Health Emergencies and Epidemic Control, Federal Ministry of Health, Khartoum, Sudan.
Wesam YousifDG of Health Emergencies and Epidemic Control, Federal Ministry of Health, Khartoum, Sudan.
Emtiaz Atta ElhusseinDG of Health Emergencies and Epidemic Control, Federal Ministry of Health, Khartoum, Sudan.
Eymanne ElBushraSudan Medical Specialization Board, Khartoum, Sudan.
Dalya EltayebDG of Primary Health Care, Federal Ministry of Health, Khartoum, Sudan.
Muntasir M O ElhassanField Epidemiology Training Program, Federal Ministry of Health, Khartoum, Sudan.
Hassan El-BushraConsultant Epidemiologist, Federal Ministry of Health, Khartoum, Sudan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Cholera is a serious public health threat, especially in fragile conflict-affected areas. Reactive oral cholera vaccine (rOCV) during outbreaks is a key response strategy recommended by the World Health Organization. Sudan implemented a large-scale reactive campaign during 2024 cholera outbreak in Kassala State. Methods: This unmatched case-control study was conducted between 6 and 26 October 2024 in Kassala locality, targeted by the national rOCV campaign using Euvichol-Plus. Data were collected through structured interviews using a pre-tested questionnaire, and analyzed in Epi Info 7 with logistic regression to estimate vaccine effectiveness and identify predictors of infection. Results: The mean age was significantly lower in cases (30.6 years, standard deviation = 20.8, Conclusions: Findings reaffirm OCV effectiveness, but emphasize the need for sustainable investment in water sanitation, and hygiene (WASH), hygiene promotion, and risk communication in fragile settings.

Indexed as

Cholera risk factors in SudanFragilityHealth emergenciesOral cholera vaccineSudan conflictVaccine effectiveness

Identifiers

PMID41704803
PMCPMC12907676

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.