Evidence map›Paper›PMID 41704775›Full record

ArticleiScience2026

Maimendong decoction suppresses non-small cell lung cancer growth by promoting dendritic cell maturation via the SIRT1/p65 acetylation pathway.

Qinfeng Zhou, Yuchen Song, Yang Guo, Yuwen Hu, Zicheng Zhang, Keke Zhao, Lijun Ai, Kaixuan Wang, Cong Wang, Lei Wang and 5 more

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Qinfeng ZhouDepartment of Laboratory Medicine, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang Hospital of Traditional Chinese Medicine, Zhangjiagang, Jiangsu 215699, China.
Yuchen SongSchool of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China.
Yang GuoMedical Experimental Research Center, First College of Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China.
Yuwen HuCenter for Inspection of JSMPA, Nanjing, Jiangsu 210026, China.
Zicheng ZhangSchool of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China.
Keke ZhaoSchool of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China.
Lijun AiSchool of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China.
Kaixuan WangSchool of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China.
Cong WangMedical Experimental Research Center, First College of Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China.
Lei WangDepartment of Laboratory Medicine, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang Hospital of Traditional Chinese Medicine, Zhangjiagang, Jiangsu 215699, China.
Lianfang LiuDepartment of Oncology, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang Hospital of Traditional Chinese Medicine, Zhangjiagang, Jiangsu 215699, China.
Li HeDepartment of Laboratory Medicine, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang Hospital of Traditional Chinese Medicine, Zhangjiagang, Jiangsu 215699, China.
Wuji JinSchool of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China.
Yong MaMedical Experimental Research Center, First College of Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, China.
Dawei CuiThe First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maimendong Decoction (MMDD), a classical traditional Chinese medicine, has shown promising clinical efficacy against non-small cell lung cancer (NSCLC), yet its immunological mechanisms remain unclear. Using a Lewis lung carcinoma (LLC) mouse model, we found that MMDD markedly suppressed tumor growth, enhanced CD8

Indexed as

ImmunologyPharmacology

Identifiers

PMID41704775
PMCPMC12907115

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.