Evidence map›Paper›PMID 41704758›Full record

ArticleiScience2026

Weixing Yan, Dong Xiang, Li Du, Di Zhu, Qi Jia, Yuting Liu, Siyu Wang, Li Liu, Haihao Guan, Yelin Zhao and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Weixing YanJiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogen Biology and Immunology, School of Basic Medical Science, Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.
Dong XiangDepartment of Dermatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221002, China.
Li DuJiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogen Biology and Immunology, School of Basic Medical Science, Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.
Di ZhuJiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogen Biology and Immunology, School of Basic Medical Science, Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.
Qi JiaJiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogen Biology and Immunology, School of Basic Medical Science, Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.
Yuting LiuJiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogen Biology and Immunology, School of Basic Medical Science, Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.
Siyu WangJiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogen Biology and Immunology, School of Basic Medical Science, Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.
Li LiuJiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogen Biology and Immunology, School of Basic Medical Science, Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.
Haihao GuanJiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogen Biology and Immunology, School of Basic Medical Science, Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.
Yelin ZhaoDepartment of Clinical Science, Intervention and Technology, Karolinska Institutet, 17165 Stockholm, Sweden.
Guan JiangDepartment of Dermatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221002, China.
Sijia GaoDepartment of Clinical Laboratory, Xuzhou Maternity and Child Health Hospital, Xuzhou, Jiangsu 221004, China.
Hui WangJiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogen Biology and Immunology, School of Basic Medical Science, Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microglia are crucial for phagocytic clearance of myelin debris, which hinders remyelination and leads to neurological decline during aging and in multiple sclerosis (MS). However, the molecular mechanism enabling microglia to expand and function effectively in remyelination remains elusive. Here, we identified that mitotic kinase Aurkb was upregulated in microglia during early development and in MS. Neonatal deletion of

Indexed as

Cell biologyNeuroscience

Identifiers

PMID41704758
PMCPMC12907124

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.