ArticleiScience2026
Biomimetic hydrogel for the construction of patient-derived bladder cancer organoids with aggressive growth.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
11 authors.
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Abstract
In cancer, the extracellular matrix (ECM) reorganization, notably collagen, forming dense, thickened, and orderly structures, affects tumor traits. Bladder cancer organoids (BCOs) mimic tumor properties for personalized medicine. However, current organoid scaffolds lack tumor-such as collagen, crucial for cell growth and migration. Previous efforts to incorporate mesoscale collagen fibers extracted directly from tumors into scaffolds were limited by the size of the tumor tissue and the efficiency of extraction. In this study, we used cellulose microfibers (MCFs) to mimic
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