Evidence map›Paper›PMID 41704725›Full record

ArticleBeilstein journal of organic chemistry2026

A mild and atom-efficient four-component cascade strategy for the construction of biologically relevant 4-hydroxyquinolin-2(1

Dmitrii A Grishin, Kseniia I Sharkovskaia, Ilya G Kolmakov, Daria A Ipatova, Rostislav A Petrov, Nikolai D Dagaev, Dmitry A Skvortsov, Maria G Khrenova, Valeriy V Andreychev, Sergei A Evteev and 4 more

Abstract read
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In one paragraph

Article in Beilstein journal of organic chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Dmitrii A GrishinDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.
Kseniia I SharkovskaiaDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.
Ilya G KolmakovDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.ORCID https://orcid.org/0009-0005-3726-8371
Daria A IpatovaDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.
Rostislav A PetrovDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.
Nikolai D DagaevDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.
Dmitry A SkvortsovDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.
Maria G KhrenovaDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.
Valeriy V AndreychevDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.
Sergei A EvteevP. Hertsen Moscow Oncology Research Institute, 2nd Botkinsky proezd, 3, 125284, Moscow, Russian Federation.
Yan A IvanenkovP. Hertsen Moscow Oncology Research Institute, 2nd Botkinsky proezd, 3, 125284, Moscow, Russian Federation.
Roman L AntipinDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.ORCID https://orcid.org/0009-0001-1864-0490
Olga А DontsovaDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.
Elena K BeloglazkinaDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.ORCID https://orcid.org/0000-0001-6796-8241

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A mild and atom-economical four-component cascade reaction has been developed, enabling the efficient and selective synthesis of previously inaccessible 4-hydroxyquinolin-2(1

Indexed as

4-hydroxyquinolin-2(1H)-oneantibacterial activityʟ-proline catalysisMeldrum’s acidMichael additionmulticomponent reaction

Identifiers

PMID41704725
PMCPMC12908358

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.