Evidence map›Paper›PMID 41704707›Full record

ReviewJournal of toxicology2026

Potential of Graphene Nanoparticles for Reducing Cadmium Toxicity and Environmental Contamination.

Alireza Ghassemi Toussi, Elham Einafshar, Sadaf Sadat Rafati

Abstract readReview
In one paragraph

Review in Journal of toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alireza Ghassemi ToussiMedical Toxicology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Razavi Khorasan, Iran, mums.ac.ir.
Elham EinafsharPharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Razavi Khorasan, Iran, mums.ac.ir.
Sadaf Sadat RafatiMedical Toxicology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Razavi Khorasan, Iran, mums.ac.ir.ORCID https://orcid.org/0009-0005-0096-0153

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This narrative review synthesizes peer-reviewed studies retrieved from major scientific databases addressing the environmental and biological applications of graphene-based nanomaterials for cadmium mitigation. Cadmium (Cd) is a nonessential and highly toxic heavy metal with a prolonged biological half-life and extensive environmental persistence, posing substantial risks to the ecosystem and human health. Exposure to cadmium is linked to nephrotoxicity, carcinogenicity, endocrine disruption, and reproductive issues. This review critically evaluates the emerging role of graphene-based nanoparticles, particularly graphene oxide (GO) and its functional derivatives, in reducing Cd bioavailability in soil, wastewater, and along the food chain. GO-based composites can achieve adsorption capacities above approximately 50-500 mg cadmium per gram of material, depending on functionalization and matrix, highlighting their substantial removal potential. Recent evidence demonstrates graphene's dual functionality: as a potent adsorbent for cadmium ions and as an enhancer of biological tolerance to cadmium-induced toxicity in both plants and human cells. To our knowledge, this review is the first to comprehensively integrate cross-disciplinary evidence on (i) the integration of engineered graphene membranes for selective filtration under pressure, (ii) GO-enhanced soil amendments that reduce cadmium uptake, (iii) thiol-functionalized composites for precise metal adsorption, and (iv) magnetic graphene nanoparticles enabling suitable cadmium removal. By integrating cross-disciplinary evidence, we provide a comprehensive roadmap for implementing graphene nanoenabled environmental interventions. Despite promising outcomes, most available evidence is based on laboratory-scale studies, with limited field-scale validation and an incomplete understanding of the long-term environmental fate and ecotoxicity of graphene nanomaterials.

Indexed as

cadmiumenvironmentalgraphene nanoparticlesnanotechnologytoxicity

Identifiers

PMID41704707
PMCPMC12907509

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.