ArticleFrontiers in medicine2026
Quantitative assessment of relative peripheral refraction in children with different refractive statuses and its associations with ocular biometry.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This study aimed to evaluate the distribution of relative peripheral refraction (RPR) and its relationship with ocular biometry in Chinese children of different refractive statuses. Methods: This study included 309 participants aged 4 to 14 years who were divided into three groups based on refraction: hyperopia, emmetropia, and myopia. IOLMaster 700 was used to acquire ocular biometry data, and RPR was measured using multispectral refraction topography. Refraction difference values (RDVs) were used to describe the RPR and included the total defocus (TRDV), defocus at 0° to 15° (RDV15), 15° to 30° (RDV15-30), 30° to 45° (RDV30-45), and 45° to 53° (RDV45-53) eccentricities, and superior (RDV-S), inferior (RDV-I), temporal (RDV-T), and nasal (RDV-N) quadrants. Results: In participants with emmetropia and myopia, RPR values became more positive as the distance from the foveal pit increased, whereas hyperopic participants showed a decrease in relative hyperopic defocus in the RDV45-53. Beyond 30° eccentricity, there were significant differences between the refractive groups; those with emmetropia and myopia had significantly higher RPR values than those with hyperopia. The spherical equivalent was negatively correlated with RDV-T ( Conclusion: In emmetropic and myopic children, RPR values became progressively positive with greater eccentricity, indicating a relative peripheral hyperopic shift. In contrast, hyperopic children showed a reduction in the RPR beyond 30° eccentricity. The spherical equivalent was negatively correlated with temporal and total RPR, and AL/R showed the strongest association with far peripheral RPR.
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