Evidence map›Paper›PMID 41704696›Full record

ArticleFrontiers in medicine2026

Case Report: Multi-sensory integration treatment for preschool children with intermittent exotropia and idiopathic scoliosis comorbidity.

Yu Huang, Zheng Li, Fanling Zeng, Yashu Li, Xidan Deng, Cheng Yang, Jin Zeng, Yanlei Chen

Abstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu Huang *Department of Ophthalmology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.
Zheng Li *Department of Ophthalmology, The Second People's Hospital of Foshan, Guangdong Pharmaceutical University, Foshan, Guangdong, China.
Fanling ZengDepartment of Rehabilitation, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.
Yashu LiDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Xidan DengNational Engineering Research Center for Healthcare Devices, Guangzhou, Guangdong, China.
Cheng YangDepartment of Ophthalmology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.
Jin Zeng *Department of Ophthalmology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.
Yanlei Chen *Department of Ophthalmology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report evaluates a novel multi-sensory integration training (MSIT) protocol, combining binocular disparate vision perception training with physiotherapeutic scoliosis-specific exercises in two pediatric patients (aged 4 and 5 years) with comorbid non-syndromic strabismus and idiopathic scoliosis. Both patients presented with intermittent exotropia, amblyopia, and thoracic scoliosis (Cobb angles of 10° and 13°, respectively). Following the individualized MSIT intervention, marked improvements were observed in both visual and spinal parameters: visual acuity of the amblyopic eye improved, exotropia magnitude decreased, stereopsis recovered, and Cobb angles substantially reduced to 3° and 0°, respectively, after 3 months. A transient "treatment plateau" in perceptual eye position metrics was observed in one case before subsequent normalization. These findings suggest that MSIT, by simultaneously addressing aberrant visual and proprioceptive inputs, effectively improves both visual function and spinal alignment in this comorbid population, potentially through promoting central nervous system recalibration of multi-sensory integration for postural control. This integrated approach highlights the importance of interdisciplinary management for children presenting with both strabismus and spinal deformities.

Indexed as

idiopathic scoliosisintermittent exotropiamulti-sensory integration training (MSIT)postural controlstrabismus

Identifiers

PMID41704696
PMCPMC12907171

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.