Evidence map›Paper›PMID 41704645›Full record

ArticleJournal of exercise science and fitness2026

The impact of accelerometer-derived 'weekend warrior' physical activity on musculoskeletal disorders and multimorbidity development.

Yuanpeng Zhu, Di Liu, Xiangjie Yin, Terry Jianguo Zhang, Nan Wu

Abstract read
In one paragraph

Article in Journal of exercise science and fitness, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuanpeng ZhuPeking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.
Di LiuPeking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.
Xiangjie YinPeking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.
Terry Jianguo ZhangPeking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.
Nan WuPeking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Whether concentrating moderate-to-vigorous physical activity (MVPA) into 1-2 days ("weekend warrior", WW) provides musculoskeletal benefits comparable to more evenly distributed weekly activity ("regular activity", RA) remains unclear. Methods: In a prospective UK Biobank accelerometer cohort (n = 52,606), participants free of musculoskeletal disease at baseline were classified hierarchically: inactive (<150 min/week MVPA); among those meeting the guideline threshold (≥150 min/week), WW (≥50% of weekly MVPA accrued within the most active 1-2 days) and RA (≥150 min/week but not meeting the WW criterion). Over a median 8.2 years of follow-up, there were 4107 osteoarthritis (OA), 2454 spine degenerative changes (SDCs), and 1006 osteoporosis (OP) events. Cox models estimated incident outcomes; multi-state models estimated transitions among baseline, first musculoskeletal disease, musculoskeletal multimorbidity (MSM), and death. Results: Compared with inactivity, both RA and WW were associated with lower risks of OA (RA hazard ratio [HR] 0.76, 95% confidence interval [CI] 0.69-0.83; WW HR 0.83, 0.77-0.89; both p < 0.001), SDCs (RA HR 0.85, 0.76-0.95, p = 0.004; WW HR 0.85, 0.78-0.94, p = 0.001), and OP (RA HR 0.74, 0.62-0.88; WW HR 0.75, 0.65-0.87; both p < 0.001). In multi-state analyses, mortality was lower versus inactivity from baseline for both RA (HR 0.61, 0.55-0.69; p < 0.001) and WW (HR 0.59, 0.54-0.65; p < 0.001), with a stronger reduction after MSM for WW (HR 0.42, 0.25-0.72; p = 0.001) than RA (HR 0.83, 0.48-1.43; p = 0.502). Conclusion: Meeting MVPA recommendations via WW may provide comparable musculoskeletal risk reduction to RA.

Indexed as

MultimorbidityMusculoskeletal disorderPhysical activity

Identifiers

PMID41704645
PMCPMC12907651

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.