Evidence map›Paper›PMID 41704608›Full record

ReviewFrontiers in oncology2026

Peritumoral edema in meningiomas: a review of influencing factors, mechanisms, and management.

Gaocai Zhang, Erman Wu, Yandong Li, Yongtao Zhang, Minghao Lian, Dangmurenjiafu Geng, Guohua Zhu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gaocai ZhangNeurosurgery Center of the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Erman WuNeurosurgery Center of the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Yandong LiNeurosurgery Center of the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Yongtao ZhangNeurosurgery Center of the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Minghao LianNeurosurgery Center of the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Dangmurenjiafu GengNeurosurgery Center of the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Guohua ZhuNeurosurgery Center of the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peritumoral brain edema is an accompanying symptom of meningiomas, and its severity impacts patient symptoms and prognosis. Meningioma-related peritumoral brain edema can result in severe symptoms such as neurological disturbance and brain herniation. Traditionally, the main treatment options for peritumoral brain edema in the perioperative period have been osmotherapy and corticosteroids, but the side effects and limited effectiveness cannot be ignored. This review summarizes the known influencing factors and mechanisms that contribute to meningioma-related brain edema, discusses the limitations of existing edema treatments, and outlines future edema treatments. More research on meningioma-related peritumoral brain edema is needed to improve patient outcomes and enhance treatment efficacy.

Indexed as

aquaporinsHIF-1mast cellsmeningiomasMMPsPTBEtenascin CVEGF

Identifiers

PMID41704608
PMCPMC12907156

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.