Evidence map›Paper›PMID 41704563›Full record

ArticleFrontiers in pharmacology2025

Edouard Cubilier, Maxime Taghavi, Eric De Prez, Lucas Jacobs, Sébastien Sinaeve, Joëlle Nortier, Marie-Hélène Antoine

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Edouard Cubilier *Nephrology Department, Brugmann University Hospital, Brussels, Belgium.
Maxime Taghavi *Nephrology Department, Brugmann University Hospital, Brussels, Belgium.
Eric De PrezLaboratory of Experimental Nephrology, Biochemistry Department, Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium.
Lucas JacobsLaboratory of Experimental Nephrology, Biochemistry Department, Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium.
Sébastien SinaeveLaboratory of Experimental Nephrology, Biochemistry Department, Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium.
Joëlle NortierNephrology Department, Brugmann University Hospital, Brussels, Belgium.
Marie-Hélène AntoineLaboratory of Experimental Nephrology, Biochemistry Department, Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pro-inflammatory and pro-thrombotic stimuli can activate endothelial cells (ECs) and predispose them to thrombotic microangiopathies (TMAs). Drug-induced TMA (DITMA) may occur in clinical practice during treatment with interferon-β1a (IFN-β1a), ciclosporin A (CsA), and gemcitabine (GEM). DITMA may also trigger the complement system and induce membrane attack complex (MAC, C5b-9) deposition

Indexed as

C5b-9ciclosporin Acomplement systemDrug-induced thrombotic microangiopathiesendothelial cellsgemcitabineinterferon-β1ain vitro

Identifiers

PMID41704563
PMCPMC12907546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.