Evidence map›Paper›PMID 41704323›Full record

ReviewJournal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures)2026

Evidence-based fluid resuscitation of the septic HFpEF patient: A narrative review of the literature.

Maxwell Ward, Roshan Acharya, Anthony Loschner

Abstract readReview
In one paragraph

Review in Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maxwell WardVirginia Polytechnic Institute and State University, Carilion School of Medicine, Roanoke, Virginia, USA.
Roshan AcharyaVirginia Polytechnic Institute and State University, Carilion School of Medicine, Roanoke, Virginia, USA.
Anthony LoschnerVirginia Polytechnic Institute and State University, Carilion School of Medicine, Roanoke, Virginia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This narrative review aims to highlight the available evidence on fluid resuscitation in septic patients with heart failure, with a particular focus on heart failure with preserved ejection fraction. Methods: A PubMed search was conducted using the keywords "sepsis" (or sepsis, or septic shock), "heart failure" (or HF, or HFrEF, or HFpEF or congestive heart failure), and "fluid" (or resuscitation, or fluid resuscitation, or fluid management). The results were summarized in narrative review format. Results/Conclusions: The presence of HFpEF in septic patients appears to be associated with an increased risk of adverse outcomes. This population may benefit from a more individualized approach to fluid resuscitation. Emerging tools for assessing fluid responsiveness and characterizing septic cardiovascular physiology show promise, but further investigation is needed.

Indexed as

fluidsheart failureHFpEFresuscitationsepsisshock

Identifiers

PMID41704323
PMCPMC12908988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.