Evidence map›Paper›PMID 41704286›Full record

SynthesisFrontiers in public health2025

LDCT uptake and determinants of lung cancer screening in Asia: a systematic review and meta-analysis.

Yue Hu, Yuntong Zhao, Pei Dong, Wuqi Qiu, Ayan Mao

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yue HuInstitute of Medical Information & Library, Chinese Academy of Medical Sciences, Beijing, China.
Yuntong ZhaoInstitute of Medical Information & Library, Chinese Academy of Medical Sciences, Beijing, China.
Pei DongInstitute of Medical Information & Library, Chinese Academy of Medical Sciences, Beijing, China.
Wuqi QiuInstitute of Medical Information & Library, Chinese Academy of Medical Sciences, Beijing, China.
Ayan MaoInstitute of Medical Information & Library, Chinese Academy of Medical Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Low-dose computed tomography (LDCT) lung cancer screening (LCS) has been shown to significantly reduce mortality rates. As its effectiveness relies on LDCT uptake, understanding uptake rates and their determinants can enhance the implementation and effectiveness of screening programs. Objective: This study aimed to analyze LDCT uptake and its influencing factors in lung cancer screening within an Asian population. Methods: Studies published between 1 January 2011 and 31 October 2025 were retrieved from four databases, and those reporting LDCT uptake and/or the factors influencing it were included. A random-effects model was applied to combine the effect estimates and 95% confidence intervals. Subgroup analyses were conducted to explore heterogeneity. Results: A total of 35 studies involving 1,716,756 participants were analyzed, yielding a pooled LDCT uptake rate for lung cancer screening of 46% (95% confidence interval [CI], 41-51%). Program-level factors included sample scale, year of LDCT uptake, and program setting ( Conclusion: LDCT uptake for lung cancer screening is lower in Asia than in academic programs, and it varies widely due to program design and population characteristics. Adopting smaller-scale screening designs and targeting key populations may help improve implementation efforts. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD42025641277, identifier CRD42025641277.

Indexed as

Early Detection of CancerLung NeoplasmsMass ScreeningTomography, X-Ray ComputedAsiaHumanscancer screeningdeterminantsLDCT uptakelung cancermeta-analysis

Identifiers

PMID41704286
PMCPMC12908593

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.