ArticleFrontiers in cardiovascular medicine2026
Zero anticoagulation, zero thrombolysis: successful management of massive pulmonary embolism following hemorrhagic transformation of acute ischemic stroke: a case report.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Background: The treatment of patients with severe pulmonary embolism complicated by intracerebral hemorrhage is challenging: anticoagulation or thrombolysis, essential for treating pulmonary embolism, can substantially worsen intracranial hemorrhage and threaten life. Case presentation: We report a case of a 78-year-old female who developed hemorrhagic transformation following acute ischemic stroke, complicated by massive pulmonary embolism and rapidly progressing to shock. In this case, emergent percutaneous mechanical thrombectomy was successfully performed under a zero-anticoagulation and zero-thrombolysis strategy, resulting in hemodynamic stabilization. Conclusion: This case provides valuable evidence supporting the feasibility of purely mechanical percutaneous intervention in high-risk, complex clinical scenarios.
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