ArticleJournal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology2026
Mucosal Melanoma of Head and Neck: A Rare and Aggressive Disease-A Register-Based Cohort Study.
Article in Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Immunohistochemical Predictors in Head and Neck Mucosal Melanoma.Head and neck pathology · 2026Article
- Case Report: Melanoma of the hard palate presenting initially with gastrointestinal symptoms: the diagnostic pivotal role ofFrontiers in medicine · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMucosal melanomas of the head and neck are rare and often diagnosed in the advanced stage. This study examines the incidence, survival and histology of mucosal melanoma compared to its cutaneous counterpart.
methodsThis register-based cohort study reviews head and neck melanomas at Helsinki University Hospital, Finland, from 2002 to 2023.
resultsA total of 56 patients with mucosal and 714 with cutaneous melanoma were reviewed. The incidence of head and neck mucosal melanoma in the region was 1.55/million/year. The most common sites for mucosal melanomas were the nose and paranasal sinuses. Mucosal melanoma was more common in women, whereas cutaneous melanoma was more common in men (p > 0.05). A significant difference emerged in mortality between mucosal and cutaneous melanoma, as 5-year survival was only 12.0% in the mucosal melanoma group compared with 60.3% in the cutaneous melanoma group.
conclusionsMucosal melanoma is a highly aggressive malignancy with poor survival; thus, prompt diagnosis is essential.
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Registered trials
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