Evidence map›Paper›PMID 41703900›Full record

ArticleExperimental physiology2026

Strain-based characterization of atrioventricular and left atrial remodelling in rat models of heart failure with preserved ejection fraction.

Qingfeng Zhang, Wenhua Li, Hongmei Zhang, Yi Wang, Lixue Yin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qingfeng ZhangSchool of Medicine, University of Electronic Science and Technology, Chengdu, China.
Wenhua LiUltrasound Medicine and Computational Cardiology Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Hongmei ZhangUltrasound Medicine and Computational Cardiology Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Yi WangUltrasound Medicine and Computational Cardiology Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Lixue YinSchool of Medicine, University of Electronic Science and Technology, Chengdu, China.

Funding

Natural Science Foundation of Sichuan Province 2023NSFSC0641Science and Technology Department of Sichuan Province 30305020569
6 · The paper itself

Abstract

Current experimental models of heart failure with preserved ejection fraction (HFpEF) lack standardized approaches for evaluating left atrial (LA) remodelling and atrioventricular (AV) coupling, leaving a critical gap in mechanistic understanding and phenotypic characterization. This study aimed to explore LA function and AV coupling status in a rat model of hypertension-related HFpEF, thereby providing support for phenotype-specific therapeutic strategies. We established two experimental rat models: A dual-hit model (high-fat diet combined with N

Indexed as

Atrial RemodelingHeart AtriaHeart FailureStroke VolumeAnimalsAtrial Function, LeftDisease Models, AnimalEchocardiographyHypertensionMaleRatsRats, Inbred DahlVentricular Remodelingatrioventricular couplingheart failure with preserved ejection fractionhypertensionleft atriumspeckle‐tracking echocardiography

Identifiers

PMID41703900
PMCPMC13140556

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.