Evidence map›Paper›PMID 41703733›Full record

Trial reportDental traumatology : official publication of International Association for Dental Traumatology2026

Effects of Photobiomodulation Therapy in Lateral Luxation of Anterior Permanent Teeth: A Randomized, Double-Blind Clinical Trial.

Flávia Monari Belmonte, Pedro Cardoso Soares, Luciane Hiramatsu Azevedo, Celso Luiz Caldeira, Patrícia Moreira de Freitas

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Dental traumatology : official publication of International Association for Dental Traumatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. New Frontiers in Dental Traumatology: Innovation, Prevention, and Clinical Practice.Dental traumatology : official publication of International Association for Dental Traumatology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Flávia Monari BelmonteSpecial Laboratory of Lasers in Dentistry, School of Dentistry, Universidade de São Paulo, São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-7668-5822
Pedro Cardoso SoaresSpecial Laboratory of Lasers in Dentistry, School of Dentistry, Universidade de São Paulo, São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-6085-783X
Luciane Hiramatsu AzevedoSpecial Laboratory of Lasers in Dentistry, School of Dentistry, Universidade de São Paulo, São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-9481-0108
Celso Luiz CaldeiraSpecial Laboratory of Lasers in Dentistry, School of Dentistry, Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Patrícia Moreira de FreitasSpecial Laboratory of Lasers in Dentistry, School of Dentistry, Universidade de São Paulo, São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-9508-6369

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmong the traumatic dental injuries (TDIs), lateral luxation may present poor prognosis due to frequent root resorption and consequent tooth loss. Photobiomodulation therapy (PBMT) modulates cellular activities (proliferation, differentiation, growth factor secretion) and may improve outcomes.

objectiveThis randomized, double-blind, placebo-controlled trial evaluated PBMT (660 vs. 808 nm) for post-operative pain and pulp sensitivity recovery in lateral luxation of permanent anterior teeth.

methodsInitially, 41 patients were included, with a total of 63 teeth traumatized by lateral luxation and were allocated to G1 (n = 21): Splinting + sham PBM (placebo), G2 (n = 21): Splinting + 808 nm infrared PBM and G3 (n = 21): Splinting + 660 nm red PBM. Four weekly sessions (3 J/point, 3 points) were administered. Pain (by numeric rating scale) and pulp sensitivity (by cold test) were assessed weekly. Pain was analyzed using the Kruskal-Wallis test, followed by multiple comparisons using Dunn's method with Bonferroni correction, and pulp sensitivity by a logistic regression model (p < 0.05).

resultsThree participants (total of 5 teeth) were excluded due to loss to follow-up. Fifty-eight teeth were analyzed (G1 = 21, G2 = 17, G3 = 20). Pain: All groups showed a significant reduction in pain over time (p < 0.001). Both G2 and G3 demonstrated a significantly greater reduction in pain compared to G1 (p < 0.001 and p = 0.026, respectively). No significant difference in pain reduction was observed between G2 and G3. Pulp sensitivity: G2 showed a significant improvement over time (p < 0.001), despite starting from a more unfavorable baseline. In contrast, no significant change in pulp sensitivity was observed for G1 or G3 between the initial and final assessments.

conclusionWithin the limitations of this clinical study, all intervention groups were effective in reducing pain in lateral luxation of permanent anterior teeth, with superior results for laser groups compared to the placebo. However, only the 808 nm laser irradiation protocol demonstrated a significant improvement in pulp sensitivity, suggesting it may offer a more complete therapeutic response.

Indexed as

IncisorLow-Level Light TherapyTooth AvulsionAdultDentin SensitivityDouble-Blind MethodFemaleHumansMalePain MeasurementPostoperative PainRed LightTreatment OutcomeYoung Adult

Identifiers

PMID41703733
PMCPMC13568944

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.