Evidence map›Paper›PMID 41703638›Full record

ArticleBMC research notes2026

Fermented botanical product supports lignin development and suppresses soil-borne pathogens.

Yuri Mizuno, Akiko Hida, Chika Tadokoro, Junichi Kato, Yasuhide Asano, Yusuke Tateuchi, Kotaro Fujioka, Shinsuke Kishida, Hideto Torii

Abstract read
In one paragraph

Article in BMC research notes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuri MizunoDepartment of Research and Development, Manda Fermentation Co., Ltd, 5800-121 Innoshima Shigei-cho, Onomichi, Hiroshima, 722-2102, Japan. yuri_mizuno@manda-kohso.co.jp.
Akiko HidaProgram of Biotechnology, Graduate School of Integrated Sciences for Life, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima, 739-8530, Japan.
Chika TadokoroProgram of Biotechnology, Graduate School of Integrated Sciences for Life, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima, 739-8530, Japan.
Junichi KatoProgram of Biotechnology, Graduate School of Integrated Sciences for Life, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima, 739-8530, Japan.
Yasuhide AsanoDepartment of Research and Development, Manda Fermentation Co., Ltd, 5800-121 Innoshima Shigei-cho, Onomichi, Hiroshima, 722-2102, Japan.
Yusuke TateuchiDepartment of Research and Development, Manda Fermentation Co., Ltd, 5800-121 Innoshima Shigei-cho, Onomichi, Hiroshima, 722-2102, Japan.
Kotaro FujiokaDepartment of Research and Development, Manda Fermentation Co., Ltd, 5800-121 Innoshima Shigei-cho, Onomichi, Hiroshima, 722-2102, Japan.
Shinsuke KishidaDepartment of Research and Development, Manda Fermentation Co., Ltd, 5800-121 Innoshima Shigei-cho, Onomichi, Hiroshima, 722-2102, Japan.
Hideto ToriiDepartment of Research and Development, Manda Fermentation Co., Ltd, 5800-121 Innoshima Shigei-cho, Onomichi, Hiroshima, 722-2102, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSoil-borne plant pathogens are a significant cause of economic loss in global agriculture. In a previous study, fermented botanical product (FBP) treatment was shown to suppress bacterial wilt disease caused by Ralstonia pseudosolanacearum (Rps) in tomatoes. This study evaluated whether treatment with FBP suppresses soil‑borne bacterial pathogens and induces host plant defense responses.

resultsSeedlings of three Solanaceae species and nine families of plants treated with water or FBP for 48 h were inoculated with Rps and wilting symptoms were compared 14 days post inoculation. FBP treated plants showed an increase in the number of individuals without wilting symptoms and a decrease in the number of dead individuals. In addition, inoculation with C. michiganensis subsp. michiganensis, which belongs to the same soil-borne bacterial disease group, showed similar suppression in tomatoes treated with FBP. To further confirm the root defense response to FBP treatment, we analyzed the amount of lignin, which is known to be a physical barrier against pathogens, and found that FBP application increased the amount of lignin in Solanaceae plants. These results suggest that FBP suppress soil-borne bacterial diseases by supporting lignin development.

Indexed as

LigninPlant DiseasesRalstoniaSoil MicrobiologySolanum lycopersicumFermentationPlant RootsSeedlingsLigninClavibacter michiganensis subsp. michiganensisFermented botanical productLigninRalstonia pseudosolanacearum

Identifiers

PMID41703638
PMCPMC13015045

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.