Evidence map›Paper›PMID 41703630›Full record

ArticleTrials2026

Comparison of plyometric training using differential learning versus nonlinear pedagogy on functional, biomechanical factors in athletes at high risk of A. C. L. injury: protocol for aparallel-group randomized controlled trial.

Majid Hamoongard, Malihe Hadadnezhad, Hassan Sadeghi, Mehdi Khaleghi Tazji, Anne Benjaminse

Abstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Majid HamoongardDepartment of Biomechanics and Sports Injuries, Faculty of Physical Education and Sports Sciences, Kharazmi University, Tehran, Iran. majidhamoongard@gmail.com.ORCID http://orcid.org/0000-0002-4175-6088
Malihe HadadnezhadDepartment of Biomechanics and Sports Injuries, Faculty of Physical Education and Sports Sciences, Kharazmi University, Tehran, Iran.ORCID http://orcid.org/0000-0002-5826-1524
Hassan SadeghiDepartment of Biomechanics and Sports Injuries, Faculty of Physical Education and Sports Sciences, Kharazmi University, Tehran, Iran.ORCID http://orcid.org/0000-0002-5602-1754
Mehdi Khaleghi TazjiDepartment of Biomechanics and Sports Injuries, Faculty of Physical Education and Sports Sciences, Kharazmi University, Tehran, Iran.ORCID http://orcid.org/0000-0002-3043-3961
Anne BenjaminseDepartment of Human Movement Sciences, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0001-8528-1136

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of anterior cruciate ligament (ACL) ruptures is notably high among young athletes participating in ball sports. Injury prevention strategies have recently emphasized the integration of multidimensional training with motor learning approaches. Emerging evidence suggests that integrating movement variability effectively reduces modifiable risk factors for ACL injuries. This study aimed to compare the effects of integrating plyometric training with either non-linear pedagogy (NLP) or differential learning (DL) on functional performance and biomechanical risk factors in athletes at high risk of ACL injury.

methodsThis single-assessor blind randomized controlled trial will include 48 male athletes (aged 18-26 years) identified as being at high risk for ACL injury. Participants will be randomly allocated to one of three groups: (1) NLP combined with plyometric training (n = 16; 24 intervention sessions over 8 weeks, three sessions per week); (2) DL combined with plyometric training (n = 16; 24 intervention sessions over 8 weeks, three sessions per week); or (3) a control group. outcome assessors will be blinded to their group allocation. The primary outcomes will include kinematic and kinetic variables, while secondary outcomes will assess functional performance. All outcomes will be measured at baseline and following the 8-week intervention period. DISCUSSION: This protocol can be an effective and innovative injury prevention strategy for athletes at high risk of an ACL injury. Designed for practical application in both clinical and field settings, the protocol incorporates plyometric exercises performed under variable conditions. Physiotherapists, athletic trainers, coaches, and return-to-sport specialists can implement it to mitigate the risk of injury.

trial registrationThe study was prospectively registered with the Iranian Registry of Clinical Trials (IRCT) on March 15, 2025, under the identifier IRCT20210602051477N3 ( https://www.irct.ir/trial/69146 ).

Indexed as

Anterior Cruciate Ligament InjuriesAthletesAthletic InjuriesLearningPlyometric ExerciseAdolescentAdultBiomechanical PhenomenaHumansMaleNonlinear DynamicsRandomized Controlled Trials as TopicRisk FactorsSingle-Blind MethodTime FactorsTreatment OutcomeACL injury risk researchEcological constraintsMotor learning strategyNonlinear dynamicsPlyometric training

Identifiers

PMID41703630
PMCPMC13015087

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.