Evidence map›Paper›PMID 41703537›Full record

Trial reportBMC oral health2026

Comparison of computer-controlled versus conventional local anesthesia delivery systems: a randomized clinical trial.

Vinesa Gill, Shahid Islam, Muhammad Ali, Jiand Malik, Talha Tanveer, Azam M Aliuddin, Aiman Zehra, Abubakar Sheikh

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vinesa GillDepartment of Operative Dentistry and Endodontics, Fatima Jinnah Dental College Hospital, 100 Feet Road, Azam Town Near DHA Phase 1, Karachi, Pakistan.
Shahid IslamDepartment of Operative Dentistry and Endodontics, Fatima Jinnah Dental College Hospital, 100 Feet Road, Azam Town Near DHA Phase 1, Karachi, Pakistan. shahidislam14@gmail.com.
Muhammad AliDepartment of Operative Dentistry and Endodontics, Fatima Jinnah Dental College Hospital, 100 Feet Road, Azam Town Near DHA Phase 1, Karachi, Pakistan.
Jiand MalikDepartment of Operative Dentistry, Mehran Medical College, Kech, Pakistan.
Talha TanveerDepartment of Prosthodontics, Baqai Dental College, Karachi, Pakistan.
Azam M AliuddinDepartment of Operative Dentistry and Endodontics, Fatima Jinnah Dental College Hospital, 100 Feet Road, Azam Town Near DHA Phase 1, Karachi, Pakistan.
Aiman ZehraFatima Jinnah Dental College Hospital, Karachi, Pakistan.
Abubakar SheikhDepartment of Operative Dentistry and Endodontics, Fatima Jinnah Dental College Hospital, 100 Feet Road, Azam Town Near DHA Phase 1, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPain perception during dental procedures is a common cause of patient anxiety. The aim of this study was to compare the pain perception during anesthetic injection and patient preference between a conventional local anesthesia technique and a computer-controlled local anesthesia delivery (CCLAD) system.

methodsA randomized, crossover clinical trial was conducted with 40 patients who received both conventional and computerized local anesthesia using the SOGA Smart II device. A 2% lidocaine with epinephrine (1.8 ml, 1:100,000) was used for both techniques. In maxilla, infiltration technique was used and in mandible, Inferior Alveolar Nerve Block was administered. The pain during injection was assessed using a Visual Analogue Scale (VAS). Statistical analysis was performed using paired t-tests.

resultsThe mean VAS score for conventional anesthesia was 4.20 ± 1.16, and for the CCLAD system was 2.23 ± 1.23. The difference was statistically significant (p < 0.001). No gender-based differences in VAS scores were observed. The majority of patients expressed a preference for the computerized system.

conclusionThe SOGA Smart II CCLAD system significantly reduces pain perception compared to conventional techniques. Most patients favored the electronic delivery method, suggesting its potential role as a patient-centered approach to reducing injection-related discomfort in selected clinical settings.

trial registrationTrial was registered retrospectively with the registration number: TCTR20250517004, dated 17th May, 2025.

Indexed as

Anesthesia, DentalAnesthetics, LocalDrug Delivery SystemsDrug Therapy, Computer-AssistedAdultAnesthesia, LocalCross-Over StudiesEpinephrineFemaleHumansInjectionsLidocaineMaleMiddle AgedNerve BlockPain MeasurementAnesthetics, LocalEpinephrineLidocaineComputer controlled local anesthesiaConventional anesthesiaL.APain perceptionRoot canal treatment

Identifiers

PMID41703537
PMCPMC13019918

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.