ArticleJournal of applied clinical medical physics2026
RapidArc Dynamic (RAD) multi-mechanical axis optimization achieves enhanced OAR sparing in cervical cancer: A dosimetric comparison study.
Article in Journal of applied clinical medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Automated decision support tool for static angle modulated ports configuration in VMAT with dynamic collimator rotation for head and neck cancer.Journal of applied clinical medical physics · 2026Article
- RapidArc Dynamic (RAD) multi-mechanical axis optimization achieves enhanced OAR sparing in cervical cancer: A dosimetric comparison study.Journal of applied clinical medical physics · 2026Article
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12 authors.
Funding
Abstract
purposeTo overcome limitations of conventional VMAT for cervical cancer, specifically restricted OAR sparing due to static collimators and delivery constraints inherent to dynamic modulation, we systematically evaluate RapidArc Dynamic (RAD) technology. This first comprehensive assessment focuses on RAD's multi-axis coordination for optimized pelvic radiotherapy planning.
methodsTwenty cervical cancer patients treated with TrueBeam whose energy was 6MV X-ray were retrospectively analyzed. The prescription was 45 Gy/25Fractions. Seven RAD-based planning strategies with varying collimator rotation modes (Optimize [OPT] vs. Optimize Between Static Angles [OBSA] vs. Static [STAT]) and aperture sizes (15 vs. 30 cm) and different static angle ports were developed using identical optimization objectives. Re-optimized clinical plan using Eclipse v18.1. All RAD and clinical plans were normalized so that the target received a certain dose with 95% target coverage for final dosimetric comparison. Dosimetric comparisons employed ANOVA (with LSD post hoc) for parametric data or Kruskal-Wallis's test (with Mann-Whitney U post hoc) for non-parametric data, with significance set at p < 0.05.
resultsRAD plans showed slightly inferior conformity and homogeneity compared to clinical plans, they achieved superior dose fall-off gradients. RAD's advantage was particularly evident in sparing organs at risk (OARs). Specifically, for the bladder, significant reductions were noted in
conclusionThe preliminary exploration of RAD plans reveals superior capability in sparing the doses of OARs. Moreover, in the RAD plans, the optimization of collimator angles and aperture at 15 cm yields better dosimetric outcomes. Therefore, further exploration of different mechanical axis combinations is of great significance in future studies.
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