Evidence map›Paper›PMID 41703179›Full record

ArticleEJNMMI physics2026

Clinical value of artificial intelligence in reducing PET image acquisition time: routine clinical validation using qualitative, quantitative, and radiomic analysis on a cohort of 282 patients undergoing [

A Dambrain, M Lacombe, P A Dufour, F Lacoeuille, O Morel, A Testard, C Bouron, S Girault, C Guillerminet

Abstract read
In one paragraph

Article in EJNMMI physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

A DambrainCRCI2NA- Inserm UMR1307/CNRS UMR 6075, University of Angers, University Hospital of Angers, Angers, France. abel.dambrain@chu-angers.fr.ORCID http://orcid.org/0009-0007-3570-4728
M LacombeDepartment of nuclear medicine, Paul Papin Center, Institut de Cancérologie de l'Ouest (ICO), Angers, France.
P A DufourDepartment of nuclear medicine, Paul Papin Center, Institut de Cancérologie de l'Ouest (ICO), Angers, France.
F LacoeuilleCRCI2NA- Inserm UMR1307/CNRS UMR 6075, University of Angers, University Hospital of Angers, Angers, France.
O MorelDepartment of nuclear medicine, Paul Papin Center, Institut de Cancérologie de l'Ouest (ICO), Angers, France.
A TestardDepartment of nuclear medicine, Paul Papin Center, Institut de Cancérologie de l'Ouest (ICO), Angers, France.
C BouronDepartment of nuclear medicine, University Hospital of Angers, Angers, France.
S GiraultDepartment of nuclear medicine, Paul Papin Center, Institut de Cancérologie de l'Ouest (ICO), Angers, France.
C GuillerminetDepartment of Medical Physics, Paul Papin Center, Institut de Cancérologie de l'Ouest (ICO), Angers, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReducing acquisition time in PET/CT imaging can degrade image quality and may compromise both diagnostic reliability and the robustness of radiomic features. This study investigates, in a large clinical cohort, whether AI-based denoising can preserve image quality and maintain the accuracy of quantitative and radiomic parameters in [

methodsWe reconstructed three sets of images: 100% acquisition time (R100), 75% (R75), and 50% (R50), with their respective denoised versions using SubtlePET® (S75 and S50). On a NEMA phantom, we analysed six contrasts (12:1-2:1) using [

resultsThe phantom study showed no difference in sphere contrast, a reduction in background noise variability, and excellent preservation of radiomic features. In the clinical population, S75 images showed improvements across all criteria evaluated, except for diagnostic confidence, which remained higher with R75 (p = 0.555 when compared to R100) for [

conclusionsSubtlePET® improves the image quality of PET acquisitions performed with reduced acquisition times using [

Indexed as

AIArtificial intelligenceDenoisingPETRadiomicsSubtlePET®

Identifiers

PMID41703179
PMCPMC13022090

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.