Evidence map›Paper›PMID 41703106›Full record

ArticleScientific reports2026

Pharmacological inhibition of hydrogen sulfide production mitigates constipation in a type 1 diabetes mouse model.

Razieh Kazemzadeh, Mohammad Badavi, Annahita Rezaie, Akram Ahangarpour, Feryal Savari, Mohammad Savari, Seyyed Ali Mard

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Razieh KazemzadehPersian Gulf Physiology Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Mohammad BadaviPersian Gulf Physiology Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Annahita RezaieDepartment of Pathobiology, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Akram AhangarpourPersian Gulf Physiology Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Feryal SavariDepartment of Medical Basic Sciences, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran.
Mohammad SavariDepartment of Microbiology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Seyyed Ali MardPersian Gulf Physiology Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Alimard77@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Constipation due to colonic contractility disorders is the predominant gastrointestinal symptom in diabetics. Hydrogen sulfide (H

Indexed as

AlkynesConstipationDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 1DisulfiramGlycineHydrogen SulfideAnimalsColonCystathionine beta-SynthaseCystathionine gamma-LyaseDisease Models, AnimalMaleMiceAlkynesCystathionine beta-SynthaseCystathionine gamma-LyaseDisulfiramGlycineHydrogen SulfidepropargylglycineConstipationDiabetesDisulfiramH2SMicePAG

Identifiers

PMID41703106
PMCPMC13004875

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.