ArticleScientific reports2026
Ultra-high resolution multimodal MRI densely labelled holistic structural brain atlas.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Regional Brain Volume Variation Across Adulthood: A Cross-Sectional MRI Analysis of Age, Sex, and Hemispheric Asymmetry.Life (Basel, Switzerland) · 2026Article
- CardioMorph Atlas: a statistical approach to evaluate association between pulmonary tuberculosis and cardiac morphology from chest X-rays.EBioMedicine · 2026Article
- Robust deep MRI contrast synthesis using a prior-based and task-oriented 3D network.Imaging neuroscience (Cambridge, Mass.) · 2025Article
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Authors and funding
19 authors.
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Abstract
In this paper, we introduce a novel structural holistic Atlas (holiAtlas) of human brain anatomy based on multimodal and high-resolution MRI that covers several anatomical levels from the organ level to the substructure level, using a new protocol for dense labelling generated from the fusion of multiple local protocols at different scales. This atlas was constructed by averaging images and segmentations of 75 healthy subjects from the Human Connectome Project database. Specifically, 3T MR images of T1, T2 and WMn (White Matter nulled) contrasts at 0.125 mm3 resolution were selected for this project. The images of these 75 subjects were nonlinearly registered and averaged using symmetric group-wise normalisation to construct the atlas. At the finest level, the proposed atlas has 350 different labels derived from 7 distinct delineation protocols. These labels were grouped at multiple scales, offering a coherent and consistent holistic representation of the brain across different levels of detail. This multiscale and multimodal atlas can be used to develop new ultra-high-resolution segmentation methods, potentially improving the early detection of neurological disorders. We make it publicly available to the scientific community.
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