ArticlePoultry science2026
Emerging zoonotic risks: whole-genome sequencing reveals antimicrobial resistance and genomic diversity in Providencia stuartii isolated from broiler chickens in Noakhali, Bangladesh.
Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Providencia stuartii is emerging as an Extensively Drug-Resistant (XDR) pathogen commonly found in animals, insects, and in burned and immunocompromised conditions. The misuse of antibiotics in poultry feed causes the emergence of XDR bacteria in the poultry industry. The knowledge of zoonotic transmissibility of poultry-derived P. stuartii remains elusive in Noakhali, Bangladesh. Poultry fecal and rectal swab samples were collected from selected farms in Noakhali, Bangladesh. Bacterial isolation and identification were performed using MacConkey agar, biochemical tests, and 16S rRNA Sanger sequencing. Antimicrobial susceptibility was assessed by the Kirby-Bauer disk diffusion method, and isolates with high multiple antibiotic resistance (MAR) indices were selected for whole-genome sequencing (WGS). Quality control, genome assembly, annotation, gene identification, pan-genome analysis, pathogenicity profiling, and comparative proteome analyses were subsequently conducted. Antibiogram analysis showed that ps_nstu_001 and ps_nstu_002 were resistant to 17 and 13 tested antibiotics, respectively. Furthermore, whole-genome sequencing revealed that both strains harbored resistance determinants to aminoglycosides, tetracyclines, sulfonamides, cephalosporins, β-lactams, and carbapenems. Additionally, mobile genetic elements (MGEs) and plasmids were identified, which represent the horizontal gene transfer capability. Moreover, pangenome analysis revealed ongoing gene acquisition and substantial genomic diversity among the isolates. The isolate ps_nstu_001 was identified as a putative human pathogen and clustered closely with a clinical strain isolated in the United States. In contrast, ps_nstu_002 was predicted to be a non-human pathogen; however, it exhibited a clear evolutionary relationship with a clinical isolate obtained from a diarrheal patient in Bangladesh, suggesting potential pathogenic relevance. Global pathogenic potential of the studied strains and key proteomic similarities between pathogenic and non-pathogenic strains revealed by pathogenicity profiling and proteome comparison. To conclude, these XDR isolates indicate the potential for zoonotic transmission and the spread of resistant genes to other animals, posing a significant public health risk.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.