Evidence map›Paper›PMID 41701946›Full record

ArticleJMIR medical education2026

AI- vs Human-Based Assessment of Medical Interview Transcripts in a Generative AI-Simulated Patient System: Cross-Sectional Validation Study.

Hiromizu Takahashi, Kiyoshi Shikino, Takeshi Kondo, Yuji Yamada, Yoshitaka Tomoda, Minoru Kishi, Yuki Aiyama, Sho Nagai, Akiko Enomoto, Yoshinori Tokushima and 5 more

Abstract readValidation Study
In one paragraph

Article in JMIR medical education, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hiromizu TakahashiDepartment of General Medicine, Faculty of Medicine, Juntendo University, 3-1-3 Hongo, Bunkyo Tokyo, 1130033 Japan, Tokyo, Japan, 81 3-3813-3111.ORCID 0000-0002-5055-7937
Kiyoshi ShikinoDepartment of Community-Oriented Medical Education, Graduate School of Medicine, Chiba University, Chiba, Japan.ORCID 0000-0002-3721-3443
Takeshi KondoCenter for Postgraduate Clinical Training and Career Development, Nagoya University Hospital, Nagoya, Japan.ORCID 0000-0002-3307-671X
Yuji YamadaBrookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.ORCID 0000-0002-5452-5334
Yoshitaka TomodaDepartment of General Internal Medicine, Itabashi Chuo Medical Center, Tokyo, Japan.ORCID 0000-0003-0115-7379
Minoru KishiDepartment of Internal Medicine, Nishiwaki Municipal Hospital, Hyogo, Japan.ORCID 0009-0001-5585-4519
Yuki AiyamaAnesthesiology and Critical Care Medicine, Tenri Hospital, Nara, Japan.ORCID 0009-0009-9608-1135
Sho NagaiDepartment of Nursing, School of Nursing, University of Human Environments, Aichi, Japan.ORCID 0009-0001-2363-1177
Akiko EnomotoDepartment of Nursing, School of Nursing, University of Human Environments, Aichi, Japan.ORCID 0009-0006-9022-2126
Yoshinori TokushimaDepartment of General Medicine, Saga University Hospital, Saga, Japan.ORCID 0009-0008-5473-9798
Takahiro ShinoharaDepartment of General Medicine, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.ORCID 0009-0000-8750-7098
Fumiaki SanoDepartment of General Medicine, Faculty of Medicine, Juntendo University, 3-1-3 Hongo, Bunkyo Tokyo, 1130033 Japan, Tokyo, Japan, 81 3-3813-3111.ORCID 0009-0001-8880-8367
Takeshi MatsuuraDepartment of General Medicine, Bibai City Hospital, Hokkaido, Japan.ORCID 0009-0007-1767-6540
Rikiya WatanabeDepartment of General Internal Medicine, Kita-Harima Medical Center, Hyogo, Japan.ORCID 0009-0007-5239-6720
Toshio NaitoDepartment of General Medicine, Faculty of Medicine, Juntendo University, 3-1-3 Hongo, Bunkyo Tokyo, 1130033 Japan, Tokyo, Japan, 81 3-3813-3111.ORCID 0000-0003-1646-9930

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Generative artificial intelligence (AI) is increasingly used in medical education, including AI-based virtual patients to improve interview skills. However, how much AI-based assessment (ABA) differs from human-based assessment (HBA) remains unclear. Objective: This study aimed to compare the quality of clinical interview assessments generated via an ABA (GPT-o1 Pro [ABA-o1] and GPT-5 Pro [ABA-5]) with those generated via an HBA conducted by clinical instructors in an AI-based virtual patient setting. We also examined whether AI reduced evaluation time and assessed agreement across participants with different levels of clinical experience. Methods: A standardized case of leg weakness was implemented in an AI-based virtual patient. Seven participants (2 medical students, 3 residents, and 2 attending physicians) each conducted an interview with the AI patient, and transcripts were scored using the 25-item Master Interview Rating Scale (0-125). Three evaluation strategies were compared. First, GPT-o1 Pro and GPT-5 Pro scored each transcript 5 times with different random seeds to test case specificity. Processing time was logged automatically. Second, 5 blinded clinical instructors independently rated each transcript once using the same rubric. Third, reliability metrics were applied. For AI, intraclass correlation coefficients (ICCs) quantified repeatability. For humans, the ICC(2,1) was calculated. Agreement was quantified using the Pearson r, Lin concordance correlation coefficient, Bland-Altman limits of agreement, Cronbach α, and ICC. Time efficiency was expressed as mean minutes per transcript and relative percentage reduction. Results: Mean interview scores were similar across methods (ABA-o1: mean 52.1, SD 6.9; ABA-5: mean 53.2, SD 6.8; HBA: mean 53.7, SD 6.8). Agreement between ABA and HBA was strong (r=0.90; concordance correlation coefficient=0.88) with minimal bias (ABA-o1: mean 0.4, SD 2.7; ABA-5: mean 1.5, SD 5.2; limits of agreement: -4.9 to 5.7 for ABA-o1 and -8.6 to 11.7 for ABA-5). The Cronbach α was 0.81 (ABA-o1), 0.86 (ABA-5), and 0.80 (HBA); the ICC(3,1) was 0.77 (ABA-o1) and 0.82 (ABA-5); and the ICC(2,1) was 0.38 (HBA). The coefficient of variation for ABA was approximately half that of HBA (6.6% vs 13.9%). Processing time for 5 runs was 4 minutes, 19 seconds for ABA-o1 and 3 minutes, 20 seconds for ABA-5 vs 10 minutes, 16 seconds for physicians, corresponding to 58% and 67.6% reductions, respectively. Conclusions: ABA-o1 and ABA-5 produced scores closely matching HBA while demonstrating superior consistency and reliability. In the setting of virtual interview transcripts, these findings suggest that ABA may serve as a valid, rapid, and scalable alternative to HBA, reducing per-assessment time by over half. Applied strategically, AI-based scoring could enable timely feedback, improve efficiency, and reduce faculty workload. Further research is needed to confirm generalizability across broader settings.

Indexed as

Artificial IntelligenceClinical CompetenceEducational MeasurementInterviews as TopicPatient SimulationAdultCross-Sectional StudiesFemaleGenerative Artificial IntelligenceHumansMaleAIartificial intelligenceChatGPTclinical interviewmedical educationsimulation-based learningvirtual patient

Identifiers

PMID41701946
PMCPMC12912650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.