ArticleThe American journal of case reports2026
Calcified Angioleiomyoma on the Dorsum of the Hand of a Patient With End-Stage Renal Disease: A Case Report.
Article in The American journal of case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND Angioleiomyoma is an uncommon benign soft-tissue tumor, typically found in the lower extremities. Angioleiomyoma is infrequently observed in the hand, and occurrences involving calcification are even less common. In patient with end-stage renal disease (ESRD) who receive hemodialysis, calcified angioleiomyoma can be challenging to distinguish diagnostically due to its resemblance to tumoral calcinosis. We report a unique case of calcified angioleiomyoma on the dorsum of the left hand in an ESRD patient undergoing long-term hemodialysis, focusing on clinical, imaging, and histopathological features. CASE REPORT A 46-year-old man, on maintenance hemodialysis for ESRD, presented with a painful, enlarging left-hand dorsal mass. Simple radiographs showed a well-defined soft-tissue mass with internal calcifications. Magnetic resonance imaging (MRI) revealed a well-circumscribed ovoid lesion with iso-intensity on the T1-weighted image and a heterogenous signal on the T2-weighted image, with no enhancement. He underwent complete marginal resection, and the histopathology confirmed angioleiomyoma with prominent dystrophic calcifications and positive smooth-muscle actin (SMA) immunostaining. No recurrence was seen at the 1-year follow-up. CONCLUSIONS This case highlights angioleiomyoma as a rare cause of painful hand nodules. Soft-tissue calcified masses must be differentiated from tumoral calcinosis and other benign tumors, especially in hemodialysis patients. Clinicopathologic and radiologic correlation are crucial for correct diagnosis and management.
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