ReviewMedical principles and practice : international journal of the Kuwait University, Health Science Centre2026
Amalgamation of Biofilms and Synthetic Biology: A Paradigm Shift in Biotechnology.
Review in Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
<p>Biofilms are intricately organized microbial communities enveloped in self-produced extracellular polymeric substances. They display remarkable resilience to environmental and antimicrobial stresses and adhere to various surfaces. Synthetic biology, which combines molecular biology with engineering principles, offers tools to modulate biofilm behavior for biotechnological applications and to address associated challenges. This review examines recent developments at the intersection of biofilm engineering and synthetic biology, highlighting strategies such as phage therapy, electrogenetic systems, microbial consortia design, quorum sensing regulation, genetic circuits, extracellular polymeric substances modification, and antimicrobial peptide-coated surfaces. These tools allow precise manipulation of biofilm structure, composition, and metabolic output. Biofilms are increasingly optimized for applications such as wastewater treatment, bioremediation, bioenergy, and diagnostics. Enhancements in stability and function are achieved via engineered circuits and extracellular polymeric substances adjustments, while antimicrobial approaches help control pathogenic biofilms. Despite these innovations, challenges remain, including biosafety, heterogeneity, scalability, and regulatory compliance. Continued interdisciplinary efforts are essential for translating these systems into viable technologies. </p>.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.