Evidence map›Paper›PMID 41701346›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2026

Reduced right/left ventricular blood pool T2-ratio predicts congestive heart failure after STEMI.

Felix Troger, Mathias Pamminger, Christina Tiller, Magdalena Holzknecht, Ivan Lechner, Alex Kaser, Philip Lungenschmid, Ramona Popa, Fritz Oberhollenzer, Martin Reindl and 3 more

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Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Felix TrogerUniversity Clinic of Radiology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Mathias PammingerUniversity Clinic of Radiology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Christina TillerUniversity Clinic of Internal Medicine III, Cardiology and Angiology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Magdalena HolzknechtUniversity Clinic of Internal Medicine III, Cardiology and Angiology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Ivan LechnerUniversity Clinic of Internal Medicine III, Cardiology and Angiology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Alex KaserUniversity Clinic of Internal Medicine III, Cardiology and Angiology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Philip LungenschmidUniversity Clinic of Radiology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Ramona PopaDepartment of Radiology and Medical Imaging, Clinical Emergency County Hospital of Brașov, Bulevardul 15 Noiembrie 60, 500326, Brașov, Romania.
Fritz OberhollenzerUniversity Clinic of Internal Medicine III, Cardiology and Angiology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Martin ReindlUniversity Clinic of Internal Medicine III, Cardiology and Angiology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Bernhard MetzlerUniversity Clinic of Internal Medicine III, Cardiology and Angiology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Sebastian J ReinstadlerUniversity Clinic of Internal Medicine III, Cardiology and Angiology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Agnes MayrUniversity Clinic of Radiology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria. a.mayr@i-med.ac.at.ORCID http://orcid.org/0000-0001-9363-873X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundT2-mapping of the blood-pool in cardiac magnetic resonance imaging (CMR) provides important information on blood-oxygenation, and differences between right and left ventricular (RV/LV) T2-relaxation times are linked to exercise capacity in heart failure. However, there are no data available on RV/LV T2-ratio after ST-segment elevation myocardial infarction (STEMI). Our aim was to investigate the prognostic value of RV/LV T2-ratio for the development of newly diagnosed congestive heart failure (CHF) post-STEMI.

methodsSix hundred four patients were enrolled after revascularized first-time STEMI; all patients underwent CMR within four days afterwards (interquartile range (IQR) 2-5). T2 relaxation times were measured in the RV and LV blood pool on short-axis T2-maps; T2-ratio was calculated as T2

resultsMedian T2-ratio was 73% (IQR 65-80) and significantly lower in patients with newly diagnosed CHF (69% vs. 73%, p = 0.019). Dichotomized at 60% (10th percentile), patients with a reduced T2-ratio experienced CHF significantly more often (19% vs. 6%, p < 0.001) and sooner (55 vs. 485 days, p < 0.001) and were significantly older, had larger infarcts, higher peak troponin T, N-terminal pro-brain natriuretic peptide (NT-proBNP), lower LV-/RV-ejection fraction, and more commonly microvascular injuries (all p < 0.05). In logistic regression, T2-ratio < 60% emerged as an independent prognostic marker in multiparametric models including classic CHF risk factors. Addition of RV/LV T2-ratio to NT-proBNP resulted in a net reclassification improvement of 0.32 (95% CI 0.06-0.57, p = 0.016).

conclusionCMR-derived RV/LV T2-ratio is an easily applicable tool bearing prognostic potential for CHF after STEMI.

Indexed as

Heart FailureHeart VentriclesMagnetic Resonance Imaging, CineST Elevation Myocardial InfarctionVentricular Function, LeftVentricular Function, RightAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPredictive Value of TestsPrognosisCardiac magnetic resonance imagingCongestive heart failureMyocardial infarctionT2-mapping

Identifiers

PMID41701346
PMCPMC13562305

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.