ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2026
Morphometric changes after endoscopic third ventriculostomy: a pediatric-adult comparison.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeEndoscopic third ventriculostomy (ETV) is an established treatment for triventricular hydrocephalus (TVH) caused by aqueductal stenosis (AqS) or mass lesions and is also applied in longstanding overt ventriculomegaly of adults (LOVA). This study aimed to compare morphometric remodeling on magnetic resonance imaging (MRI) after ETV between pediatric and adult patients.
methodsThis retrospective single-center study included 67 patients with TVH or LOVA (patent aqueduct), stratified into children with AqS (n = 21), adults with AqS (n = 24), adults with lesions (n = 12), and adults with LOVA (n = 10). Mamillopontine distance (MPD), Evans' index (EI), and third ventricle diameter (D3V) were measured preoperatively, postoperatively, and at follow-up. Longitudinal changes were compared within and between groups.
resultsFollow-up MRI was available in 88.1% (n = 59/67). No child required shunt placement, compared with 12.5% of adults with AqS, 8.3% with lesions, and 30% with LOVA. Morphometric analysis revealed significant improvement (p < 0.05) in MPD, EI, and D3V from baseline to follow-up in children and adults with AqS. Adults with lesions showed significant changes only in MPD and D3V, whereas adults with LOVA exhibited no significant differences. Between-group analyses confirmed the most distinct and consistent ventricular remodeling in pediatric patients.
conclusionChildren demonstrated the most pronounced morphometric response after ETV, reflecting more effective ventricular remodeling than in adults. These findings suggest a stronger cerebrospinal fluid dynamic adaptation in pediatric patients, which may contribute to more favorable long-term outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.