Evidence map›Paper›PMID 41701317›Full record

Observational studyGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026

Functional assessment of the Preserflo MicroShunt implant in pigmentary glaucoma: 2 years follow-up.

M García-Bermúdez, J García-Bardera, M A Pascual-Santiago, P Robles-Amor, L Morales-Fernández, N Güemes-Villahoz, C D Méndez-Hernández, S García-Saénz, J M Martínez-de-la-Casa, J García-Feijoo

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Preserflo microshunt outcomes in pigmentary glaucoma: a propensity score-matched comparison with primary open-angle glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

M García-BermúdezOphthalmology unit, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Profesor Martin Lagos SN, 28040, Madrid, Spain. mireia.gabe@gmail.com.ORCID 0009-0005-2449-9330
J García-BarderaOphthalmology unit, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Profesor Martin Lagos SN, 28040, Madrid, Spain.
M A Pascual-SantiagoOphthalmology unit, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Profesor Martin Lagos SN, 28040, Madrid, Spain.
P Robles-AmorOphthalmology unit, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Profesor Martin Lagos SN, 28040, Madrid, Spain.
L Morales-FernándezOphthalmology unit, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Profesor Martin Lagos SN, 28040, Madrid, Spain.
N Güemes-VillahozOphthalmology unit, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Profesor Martin Lagos SN, 28040, Madrid, Spain.
C D Méndez-HernándezOphthalmology unit, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Profesor Martin Lagos SN, 28040, Madrid, Spain.
S García-SaénzOphthalmology unit, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Profesor Martin Lagos SN, 28040, Madrid, Spain.
J M Martínez-de-la-CasaOphthalmology unit, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Profesor Martin Lagos SN, 28040, Madrid, Spain.
J García-FeijooOphthalmology unit, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Profesor Martin Lagos SN, 28040, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the clinical outcomes of Preserflo MicroShunt (PMS) implantation with mitomycin C (MMC) in the management of pigmentary glaucoma (PG).

methodsRetrospective observational study. All consecutive patients diagnosed with PG who underwent PMS implantation with at least 24 months of follow-up were included. Primary outcomes included postoperative intraocular pressure (IOP), number of hypotensive medications, surgical success, defined as IOP < 18 mmHg with a reduction of ≥ 20% from baseline without the need for further surgery and no severe surgery-related complications. ‘Complete success’ was defined as achieving target IOP without medications; ‘qualified success’ allowed the use of medications.

resultsFourteen eyes from 10 patients (mean age 60.8 ± 11.8 years) were included. Mean IOP was significantly reduced from 23.8 ± 6.0 mmHg at baseline to 14.9 ± 4 mmHg at 12 months and to 15.4 ± 2.7 at 24 months (both p < 0.001). The mean number of glaucoma medications per patient decreased from 2.9 ± 1 at baseline to 0.5 ± 0.8 at 12 months ( p = 0.002) and to 1 ± 0.9 at 24 months (p = 0.003). At 24 months, 35.7% of patients (n = 5) were medication-free. Overall success at 12 and 24 months was 71.4%, with complete success achieved in 50% at 12 months and 28.6% at 24 months. No sight-threatening complications were observed. No cases required bleb revision.

conclusionOur results suggests that PMS is a safe and effective surgical option for the treatment of PG.

Indexed as

Glaucoma Drainage ImplantsGlaucoma, Open-AngleIntraocular PressureVisual AcuityAgedAlkylating AgentsFemaleFollow-Up StudiesHumansMaleMiddle AgedMitomycinProsthesis DesignRetrospective StudiesTime FactorsTonometry, OcularAlkylating AgentsMitomycinAb externo surgeryIntraocular pressure (IOP)MIBSMitomycin cSecondary glaucoma

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.