Evidence map›Paper›PMID 41701296›Full record

ArticleChild psychiatry and human development2026

Predictive Relations Between Early Adversity, Nonlinear Trajectories of Hypothalamic-Pituitary-Adrenal Axis Functioning, and Later Callous-Unemotional Traits.

Nicole Huth, Sarah C Vogel, Veronica Cole, W Roger Mills-Koonce, Michael T Willoughby, Nicholas J Wagner

Abstract read
PubMed Publisher
In one paragraph

Article in Child psychiatry and human development, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicole HuthDepartment of Psychological and Brain Sciences, Boston University, 64 Cummington Mall, Boston, MA, 02215, USA.
Sarah C VogelDepartment of Psychology, University of Massachusetts Boston, Boston, USA.
Veronica ColeDepartment of Psychology, Wake Forest University, Winston-Salem, USA.
W Roger Mills-KoonceSchool of Education, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Michael T WilloughbyRTI International, Research Triangle Park, USA.
Nicholas J WagnerDepartment of Psychological and Brain Sciences, Boston University, 64 Cummington Mall, Boston, MA, 02215, USA. njwagner@bu.edu.

Funding

Risky Parenting and Temperament Pathways To Callous-Unemotional Traits In Early ChildhoodR01MH125904 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Nicholas J Wagner, Rebecca Waller · 2022 to 2026
$3.9M
National Institute of Child Health and Human Development 1PO1HD39667NIMH NIH HHS R01MH125904
6 · The paper itself

Abstract

Developmental pathways to callous-unemotional (CU) traits are heterogeneous, with early social experiences and stress physiology, such as hypothalamic-pituitary-adrenal (HPA) axis functioning, likely playing key roles. However, few studies have examined how adversity and HPA axis functioning in early childhood relate to later CU traits. Using Latent Basis Growth Mixture Modeling with a longitudinal sample (N = 1,292), we examined relations between trajectories of salivary basal cortisol in early childhood (6, 15, 24, and 48 months), adversity at 6 months, and CU traits at preadolescence (M

Indexed as

AdversityCallous-unemotional traitsDevelopmental psychopathologyStress physiology

Identifiers

PMID41701296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.