Evidence map›Paper›PMID 41701230›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2026

The recurrence of osteoporotic fractures among first- and second-generation immigrants in Sweden.

Per Wändell, Xinjun Li, Hans Ranch Lundin, Axel C Carlsson, Jan Sundquist, Kristina Sundquist

Abstract read
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Per WändellDivision of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
Xinjun LiCenter for Primary Health Care Research, Lund University, Malmö, Sweden.
Hans Ranch LundinDivision of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
Axel C CarlssonDivision of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden. axel.carlsson@ki.se.
Jan SundquistCenter for Primary Health Care Research, Lund University, Malmö, Sweden.
Kristina SundquistCenter for Primary Health Care Research, Lund University, Malmö, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This nationwide cohort study compared recurrent osteoporotic fracture risk in first- and second-generation immigrants to native Swedes. First- and second-generation immigrant men had lower risks; first- and second-generation immigrant women had similar risks to native Swedes. Variations were observed by region of origin, suggesting differences in fracture susceptibility among immigrant groups. PURPOSE: To analyse the risk of a recurrent osteoporotic fracture in immigrants using Swedish-born individuals with Swedish-born parents as referents.

methodsA nationwide open cohort study including individuals ≥ 50 years of age at baseline (N = 296,118) with a previous fracture. Immigrants were classified as first- or second-generation immigrants, i.e. foreign-born or Swedish-born individuals with at least one foreign-born parent. Osteoporotic fractures were defined as at least one registered diagnosis of fractures in the hip, humerus, forearm, vertebrae, or pelvis in the National Patient Register between January 1, 2010, and December 31, 2018. Logistic regression analysis estimated odds ratios (ORs) with 95% confidence intervals (95% CI) for a second osteoporotic fracture in individuals with a first osteoporotic fracture. Logistic regression models were stratified by sex and adjusted for age, comorbidities, and sociodemographic status.

resultsA total of 33,172 fractures (men n = 7,428, and women n = 25,744) were registered in the first-generation study, and 12,979 (men n = 3,607 and women n = 9,372) in the second-generation study. Fully adjusted ORs (95% CI) were for all foreign-born men 0.90 (0.82-0.98) and women 0.95 (0.91-1.00), and for men with foreign-born parents 0.85 (0.73-0.99), and women 1.00 (0.91-1.09). Groups with statistically significant lower odds included men from Asia, women from Eastern Europe, Baltic countries, Asia and Latin America, and men with parents from the Nordic countries.

conclusionsAmong first- and second-generation men, the risk of a second fracture was slightly lower than that of native Swedes, while among first- and second-generation women, the risk was similar to the reference group.

Indexed as

Emigrants and ImmigrantsOsteoporotic FracturesAgedAged, 80 and overCohort StudiesFemaleHumansMaleMiddle AgedRecurrenceRegistriesRisk AssessmentRisk FactorsSex DistributionSwedenForearm fracturesGenderHumerus fractures, Hip fractures, Vertebral fracturesImmigrantsNeighbourhoodOsteoporotic fracturesSocioeconomic status

Identifiers

PMID41701230
PMCPMC13190450

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.