ReviewExpert opinion on drug metabolism & toxicology
Potential integration of multiple organs-on-a-chip for comprehensive drug-drug interaction prediction.
Review in Expert opinion on drug metabolism & toxicology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
introductionPredicting drug - drug interactions (DDIs) is essential for safe, effective medication therapy, yet conventional AREAS COVERED: We outline current DDI workflows, their strengths and limitations, and how single-organ chips can produce quantitative absorption, distribution, metabolism, and excretion (ADME) and toxicity parameters relevant for DDI analysis. We then discuss the need for emerging MOC platforms and the unique advantages that they offer, highlighting case studies that capture more complex DDI scenarios, as well as body-on-a-chip prototypes integrated with mechanistic modeling. EXPERT OPINION: MOC systems are currently poised to complement, not replace, established
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.