Evidence map›Paper›PMID 41701143›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2026

When family caregiving happens: life-course timing and health outcomes in later life.

Chioun Lee, Dana A Glei, Soojin Park, Casey K Brown, Maxine Weinstein

Abstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Gender and racial/ethnic disparities in the life-course timing of first unpaid caregiving: a survival analysis approach.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chioun LeeDepartment of Sociology, University of California, Riverside, Riverside, California, United States.ORCID 0000-0002-6886-8397
Dana A GleiCenter for Population and Health, Georgetown University, Washington, District of Columbia, United States.ORCID 0000-0002-2865-9355
Soojin ParkSchool of Education, University of California, Riverside, Riverside, California, United States.ORCID 0000-0003-0288-5589
Casey K BrownCenter for Population and Health, Georgetown University, Washington, District of Columbia, United States.
Maxine WeinsteinCenter for Population and Health, Georgetown University, Washington, District of Columbia, United States.

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
The Center for Health Improvement of Minority ElderlyP30AG021684 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Homero Erwin del Pino · 2002 to 2026
$19.7M
Network on Education, Biosocial Pathways, and Dementia across Diverse PopulationsR24AG077433 · NIA · UNIV OF MARYLAND, COLLEGE PARK · PI Sanjay Asthana, Pamela Herd · 2022 to 2026
$3.0M
Interpersonal Emotion Regulation in Neurodegenerative Disease: Pathways to Caregiver HealthR00AG073617 · NIA · GEORGETOWN UNIVERSITY · PI BROWN, CASEY LEIGH · 2022 to 2025
$1.2M
National Institute on Aging (NIA) R24AG077433National Science Foundation 2243119NIA NIH HHS P30 AG021684NIA NIH HHS R00 AG073617NIA NIH HHS R24 AG077433NIH/National Center for Advancing Translational Sciences (NCATS) UCLA Clinical and Translational Science Institute (CTSI) UL1TR001881University of California, Los Angeles Resource Center for Minority Aging Research (RCMAR) Center for Health Improvement of Minority Elders (CHIME) P30-AG021684
6 · The paper itself

Abstract

objectivesMost family caregiving research focuses on individuals in midlife and old age, when caregiving responsibilities are likely to emerge and become widespread. However, caregiving begins earlier for some individuals, particularly among those in families with limited resources or disability needs. While research on early caregiving has grown, its long-term health consequences remain understudied.

methodsUsing a life history calendar from the Health and Retirement Study (N = 12,443), we constructed caregiving histories, including onset age, duration, and caregiver-recipient relationship. We examined whether caregiving that starts earlier in life-particularly before midlife-was negatively associated with later-life mental, physical, and cognitive functioning, independent of other caregiving characteristics and early-life factors.

resultsCompared with non-caregivers, caregivers exhibited more physical limitations and higher depressive symptoms, but better cognitive function on average. Among caregivers, those who began caregiving before midlife, especially during adolescence or young adulthood, reported more physical limitations, higher depressive symptoms, and poorer cognitive function later in life. These associations remained robust after adjusting for caregiving duration and the caregiver-recipient relationship. DISCUSSION: The association between caregiving and health outcomes varies depending on when and under what circumstances caregiving occurs. This study highlights the importance of caregiving timing by demonstrating the long arm of early caregiving on later health outcomes. The finding underscores the need for targeted interventions aimed at young caregivers. Future research should investigate the life-course mechanisms through which early caregiving shapes health trajectories over time.

Indexed as

CaregiversDepressionHealth StatusAgedFemaleHumansLongitudinal StudiesMaleMiddle AgedTime FactorsEarly origins of healthHealth disparitiesLife courseLongitudinal design/data analysis

Identifiers

PMID41701143
PMCPMC13075644

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.