ArticleTechnology in cancer research & treatment
Analysis of Surface Guidance Versus Laser Alignment for Precision Lung Cancer Particle Therapy.
Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
IntroductionLung particle therapy using pencil beam scanning achieves high dose conformity but remains vulnerable to geometric uncertainties from suboptimal initial setup. Surface-guided radiotherapy (SGRT) improves setup reproducibility in photon workflows, yet evidence in lung particle therapy remains limited. This study evaluates the clinical value of SGRT in improving six degrees of freedom (6-DOF) setup reproducibility in lung cancer particle therapy.MethodsThis retrospective cohort study analyzed 63 lung cancer patients receiving 1277 treatment fractions at our center from February 2023 to January 2024. Comparisons were made between conventional laser-based positioning, which included 983 fractions, and SGRT workflows, which included 294 fractions. Following patient positioning, therapists manually registered orthogonal kilovoltage (kV) x-ray images with planning digitally reconstructed radiographs (DRRs) to calculate 6-DOF correction parameters, including translational (lateral, longitudinal, vertical) and rotational (pitch, roll, yaw) components, and to quantify the pre-correction setup error . Absolute 6-DOF displacements and three-dimensional vector magnitudes (MAG) were measured. The analysis included 36 supine patients with 739 treatment fractions and 27 prone patients with 538 fractions.ResultsThe SGRT group exhibited statistically significant reductions in median shifts for lateral (0.25 cm to 0.21 cm,
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