Evidence map›Paper›PMID 41700931›Full record

ReviewDiabetes2026

Staying Functional Through Connection and Adaptation: When Islets Inspire Islet Biologists.

Sangeeta Dhawan, Jing Hughes, Aleksey V Matveyenko, Vincent Poitout

Abstract readReview
In one paragraph

Review in Diabetes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sangeeta DhawanDepartment of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes & Metabolism Research Institute, City of Hope, Duarte, CA.ORCID 0000-0002-1562-7899
Jing HughesDepartment of Medicine, Yale School of Medicine, New Haven, CT.
Aleksey V MatveyenkoDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN.
Vincent PoitoutUniversity of Montreal Hospital Research Center, Montreal, Quebec, Canada.

Funding

Role of Circadian Misalignment in Beta-cell Failure in Type 2 DiabetesR01DK098468 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ALEKSEY V MATVEYENKO · 2013 to 2026
$5.8M
FFA4 regulation of pancreatic islet functionR01DK132597 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HUISING, MARK O., POITOUT, VINCENT · 2022 to 2025
$1.9M
Metabolic signaling of the beta cell primary ciliumR01DK140365 · NIDDK · YALE UNIVERSITY · PI Jing Wang Hughes, Matthew J. Merrins · 2024 to 2026
$1.9M
Paracrine regulation of islet cell function by primary ciliaR01DK138974 · NIDDK · YALE UNIVERSITY · PI Jing Wang Hughes · 2024 to 2026
$1.3M
Epigenetic regulation of genomic stability in beta-cell homeostasisR01DK140088 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI Sangeeta Dhawan · 2025 to 2026
$1.3M
Diabetes CanadaInstitute of Nutrition, Metabolism and Diabetes PJT-469193J.W. Kieckhefer FoundationNatural Sciences and Engineering Research Council of Canada RGPIN-2022-03732NIDDK NIH HHS R01DK098468NIDDK NIH HHS R01DK132597NIDDK NIH HHS R01DK138974NIDDK NIH HHS R01 DK140088NIDDK NIH HHS R01DK140088NIDDK NIH HHS R01DK140365
6 · The paper itself

Abstract

In response to the lockdowns and travel bans during the coronavirus disease 2019 pandemic, Peter C. Butler at the University of California, Los Angeles (UCLA), started a virtual islet biology seminar series. After the authors of this article joined him as co-organizers, this initiative became the Islet Research Seminar Series (IRSS). Like islets of Langerhans adapt to their changing environment, the islet biology community quickly embraced this new format. The IRSS evolved into a lasting scientific forum that convenes weekly and is attended by islet biologists from the U.S., Canada, Europe, and Israel. The series covers a range of topics in islet biology, with presentations from scientists representing all career stages. It has proven particularly valuable for trainees and early-stage investigators in exposing them to a variety of topics in islet biology without travel required and facilitating more spontaneous interactions with senior scientists than at in-person meetings. While the online format is not meant to replace live scientific conferences, we believe that the IRSS plays a unique role in keeping the islet biology community connected and abreast of the most recent scientific discoveries in our field. The success of this platform stands as a testament to the scientific community to adapt and thrive through challenges. This article is dedicated to Peter C. Butler, UCLA, who initiated the IRSS.

Indexed as

Islets of LangerhansAdaptation, PhysiologicalAnimalsCOVID-19HumansSARS-CoV-2

Identifiers

PMID41700931
PMCPMC13007208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.