Evidence map›Paper›PMID 41700902›Full record

ArticleACS biomaterials science & engineering2026

Construction of Peptide Amphiphile-Coated Coacervates with Selective Permeability.

Bin Wang, Kristi L Kiick, Millicent O Sullivan

Abstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bin WangDepartment of Materials Science and Engineering, University of Delaware, Newark 19716, Delaware, United States.ORCID 0000-0002-7835-7160
Kristi L KiickDepartment of Materials Science and Engineering, University of Delaware, Newark 19716, Delaware, United States.ORCID 0000-0001-8587-0301
Millicent O SullivanDepartment of Biomedical Engineering, University of Delaware, Newark 19716, Delaware, United States.ORCID 0000-0002-4787-7534

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The combination of membranes with coacervates has been regarded as an effective approach to stabilize coacervates and modify their surface properties. Here, we achieved the construction of a functional coacervate system by localizing nanovesicles assembled by elastin-like peptide-block-collagen-like peptides (ELP-CLPs) on the surface of polyelectrolyte coacervates. The formation of the ELP-CLP coating was driven by electrostatic interactions between negatively charged ELP-CLP vesicles and positively charged coacervates. Altering the surface charge of ELP-CLP vesicles or coacervates disrupted the formation of coatings, and the formulation parameters, such as different mixing protocols and the order of adding the components, could be used to control the coating process. The ELP-CLP vesicle coating successfully functionalized the coacervates and presented the ability to control the diffusion of molecules based on their different molecular weights. Our results demonstrated approaches to control the coating process and coating functionality of ELP-CLP vesicle coatings and highlighted their potential application as a novel surface modification to provide selective permeability to current coacervate systems.

Indexed as

PeptidesSurface-Active AgentsCollagenElastinPermeabilityStatic ElectricitySurface PropertiesCollagenElastinPeptidesSurface-Active Agentscharge interactionscoacervatecoatingformulationpeptide amphiphileselective permeabilityself-assemblysurface modification

Identifiers

PMID41700902
PMCPMC12976995

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.